Protein Alignment wit and babo

DIOPT Version :10

• Sequence 1: NP_001261395.1
• Gene: wit / 44096
• FlyBaseID: FBgn0024179
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_476999.1
• Gene: babo / 35900
• FlyBaseID: FBgn0011300
• Length: 622
• Species: Drosophila melanogaster
• Alignment Length: 588
• Identity: 151/588 - (25%)
• Similarity: 239/588 - (40%)
• Gaps: 141/588 - (23%)

  Fly    34 DNSFHDDDG----------DQDSSGELQEQQVESTPI----PS--EP------HRRTC------- 69
            ||..||::.          |.|:||.:........||    ||  :|      |..||
  Fly    77 DNRSHDNNNASAVSMLLPQDGDASGAVAPAVTPQLPIYIAQPSAKKPENKIKCHCDTCKESNNIC 141

  Fly    70 -PDGYTFCFTIWNQTANGARVVKQGCWKDN----TDRTSICSQSECTSSAPTSK---TSSLYYCC 126
             .||  ||||...:.::|:.:....|...:    ..|:..|:..  ....||::   .:..:.||
  Fly   142 ETDG--FCFTSVEKNSDGSIIFSYRCLHKSQIFPPGRSIWCNDG--LHGGPTARPVGRNGAHACC 202

  Fly   127 CSGGVCN------------------AQYSVVEPAPLELGSNEGRTSITNRATEKQHQSFLASTML 173
            .....||                  .|.||.:..|..|.|.|
  Fly   203 KDRDFCNRFLWPKTKDQRSDRVEEGRQISVQDYVPHRLTSWE----------------------- 244

  Fly   174 GLAGGLTALTIGIFLAV--------QYCRTAKEKPE-----PEESPLAP---------------- 209
                 ..|:.:|..|.:        .||:..|....     .|:|...|
  Fly   245 -----FVAIILGATLFICFTGTSTWYYCQRRKRMASGRTFAKEDSAYDPILNGNTTIHDIIEMTT 304

  Fly   210 SGPGYSSNL-----RNV-DNMNLIGMLGSGKYGTVMKGLLHDQEVAVKIYPEEHHQYYVNERNIY 268
            ||.| |:.|     |:: ..:.|..::|.|::|.|.:|....:.|||||:.......:..|..||
  Fly   305 SGSG-SAGLPLLVQRSIARQVQLCHVIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIY 368

  Fly   269 ALPLMECPALLSYFGYDERCTMDGRMEYQ--LVLSLAPLGCLQDWLIANTLTFSECCGMLRSITR 331
            ...::....:|.:...|.:   |.....|  ||......|.|.|:|..:.:..:....|..||..
  Fly   369 QTVMLRHENILGFIAADNK---DNGTWTQLWLVTDYHENGSLFDYLTTHPVDTNTMLNMSLSIAT 430

  Fly   332 GISHLHTELRLGDQHKPCVAHRDINTRNVLVQADLSCCIADFGFALKVFGSKYEYKGEVAMAETK 396
            |::|||.:: :|.:.||.:||||:.::|:||:::|||.|.|.|.|:     ::..|.:  ..:..
  Fly   431 GLAHLHMDI-VGTRGKPAIAHRDLKSKNILVKSNLSCAIGDLGLAV-----RHVEKND--SVDIP 487

  Fly   397 SINEVGTLRYMAPELLEGAVNLRDCETSLKQMDVYALGLVLWEVATRCSDFYAPGQATPPYKAPY 461
            |.:.|||.||||||:|:.::|.:..: |.|:.||||.||:|||:|.||:    .|.....|:.||
  Fly   488 STHRVGTKRYMAPEVLDESMNDQHFD-SYKRADVYAFGLILWEIARRCN----MGMIYDEYQLPY 547

  Fly   462 EQEVGSHPSFDQMQALVVRHKARPLFPTGWGGGAAAKVVRDTCEDCWDHDADARLTSLCAEERMQ 526
            ...|...||.::|:.:|...|.||..|..|........:....::||..:..||||:|..::.:.
  Fly   548 YDVVQPDPSIEEMKKVVCIEKCRPNIPNRWHASDVLHNMAKVMKECWYPNPVARLTALRIKKTLA 612

  Fly   527 EMS 529
            .:|
  Fly   613 SIS 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wit	NP_001261395.1	TFP_LU_ECD_Wit	25..138	CDD:467138	33/158 (21%)
		STKc_BMPR2_AMHR2	228..528	CDD:270956	95/301 (32%)
babo	NP_476999.1	TFP_LU_ECD_Babo	127..210	CDD:467127	18/86 (21%)
		GS	294..324	CDD:197743	6/30 (20%)
		STKc_TGFbR1_ACVR1b_ACVR1c	328..615	CDD:271045	95/302 (31%)