Protein Alignment wit and tkv

DIOPT Version :9

• Sequence 1: NP_001261395.1
• Gene: wit / 44096
• FlyBaseID: FBgn0024179
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_787990.1
• Gene: tkv / 33753
• FlyBaseID: FBgn0003716
• Length: 575
• Species: Drosophila melanogaster
• Alignment Length: 544
• Identity: 139/544 - (25%)
• Similarity: 223/544 - (40%)
• Gaps: 95/544 - (17%)

  Fly    41 DGDQDSSGELQEQQVEST---------PIPSEPHRRTC---PDGYTFCFT----IWNQTANGARV 89
            :|.:|:..| :.:.||:.         ..|......||   |.|  .||:    ::::|.
  Fly    62 EGYEDADNE-KSKTVENARSLTCYCDGSCPDNVSNGTCETRPGG--SCFSAVQQLYDETT----- 118

  Fly    90 VKQGCWKDNTDRTSICSQSE-------CTSSAPTSKTSSLYYCCCSGGVCNAQ-YSVVEPAPLEL 146
               |.:::  :||..|...|       |..:|..........||.....||.. |....|
  Fly   119 ---GMYEE--ERTYGCMPPEDNGGFLMCKVAAVPHLHGKNIVCCDKEDFCNRDLYPTYTP----- 173

  Fly   147 GSNEGRTSITNRATEKQHQSFLASTMLGLAGGLTALTIGIFLAVQYCRTAKEKPEPEESP----- 206
                   .:|..|.:....|....|:......:.:|::.:.:....|.|.|.:.:..:.|
  Fly   174 -------KLTTPAPDLPVSSESLHTLAVFGSIIISLSVFMLIVASLCFTYKRREKLRKQPRLINS 231

  Fly   207 -----LAP--------SGPGYSSNL---RNV-DNMNLIGMLGSGKYGTVMKGLLHDQEVAVKIYP 254
                 |:|        ||.|....|   |.: ..:.::.::|.|:||.|......|:.||||.:.
  Fly   232 MCNSQLSPLSQLVEQSSGSGSGLPLLVQRTIAKQIQMVRLVGKGRYGEVWLAKWRDERVAVKTFF 296

  Fly   255 EEHHQYYVNERNIYALPLMECPALLSYFGYDERCTMDGR---MEYQLVLSLAPLGCLQDWLIANT 316
            ......:..|..||...||....:|.:...|    :.|.   .:..|:.....:|.|.|:|..:.
  Fly   297 TTEEASWFRETEIYQTVLMRHDNILGFIAAD----IKGNGSWTQMLLITDYHEMGSLHDYLSMSV 357

  Fly   317 LTFSECCGMLRSITRGISHLHTELRLGDQHKPCVAHRDINTRNVLVQADLSCCIADFGFALKVFG 381
            :...:...:..|:..|::|||.|: .|...||.:|||||.::|:||:.:..|.|||||.|:|
  Fly   358 INPQKLQLLAFSLASGLAHLHDEI-FGTPGKPAIAHRDIKSKNILVKRNGQCAIADFGLAVK--- 418

  Fly   382 SKYEYKGEVAMAETKSINEVGTLRYMAPELLEGAVNLRDCETSLKQMDVYALGLVLWEVATRCSD 446
                |..|:.:........|||.||||||:|...::.:..| ..|:.|:|::||||||:..||
  Fly   419 ----YNSELDVIHIAQNPRVGTRRYMAPEVLSQQLDPKQFE-EFKRADMYSVGLVLWEMTRRC-- 476

  Fly   447 FYAPGQAT-----PPYKAPYEQEVGSHPSFDQMQALVVRHKARPLFPTGWGGGAAAKVVRDTCED 506
             |.|...|     ..|..||...|.|.|:|:.|.|:|.....||..|:.|........|....::
  Fly   477 -YTPVSGTKTTTCEDYALPYHDVVPSDPTFEDMHAVVCVKGFRPPIPSRWQEDDVLATVSKIMQE 540

  Fly   507 CWDHDADARLTSLCAEERMQEMST 530
            ||..:...|||:|..::.:..:.|
  Fly   541 CWHPNPTVRLTALRVKKTLGRLET 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wit	NP_001261395.1	snake_toxin	57..133	CDD:264434	17/98 (17%)
		STYKc	226..517	CDD:214568	93/298 (31%)
		STKc_BMPR2_AMHR2	228..528	CDD:270956	96/307 (31%)
tkv	NP_787990.1	Activin_recp	81..171	CDD:279413	20/101 (20%)
		GS	238..266	CDD:197743	6/27 (22%)
		S_TKc	267..557	CDD:214567	96/305 (31%)
		STKc_BMPR1	270..562	CDD:271046	96/307 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445039
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23255
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940