Protein Alignment wit and acvr2ba

DIOPT Version :10

• Sequence 1: NP_001261395.1
• Gene: wit / 44096
• FlyBaseID: FBgn0024179
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_571285.1
• Gene: acvr2ba / 30457
• ZFINID: ZDB-GENE-980526-549
• Length: 509
• Species: Danio rerio
• Alignment Length: 511
• Identity: 156/511 - (30%)
• Similarity: 257/511 - (50%)
• Gaps: 77/511 - (15%)

  Fly    71 DGYTFCFTIWNQTANGARVVKQGCWKDNTDRTSIC-SQSECTSSAPTSKTSSLYYCCCSGGVCNA 134
            |..:.|:..|...:...::||:|||.|:.:    | .:.||.:   |.:...:::|||.|..||.
Zfish    54 DKRSHCYASWRNNSGSIQLVKKGCWLDDFN----CYDRQECVA---TEENPQVFFCCCEGNFCNE 111

  Fly   135 QYS--------VVEPAPLELGSNEGRTSITNRATEKQHQSFLASTMLGLAGGLTALTIGIFLAVQ 191
            :::        |:.|.|:.       .|:.|         .|..::|    .|:.|::.:.||..
Zfish   112 RFTHLPDISGPVISPPPVS-------PSLLN---------VLVYSLL----PLSMLSMAVLLAFW 156

  Fly   192 YCRTAKEKP-----EPEESPLAPSGPGYSSNLRNVDNMNLIGMLGSGKYGTVMKGLLHDQEVAVK 251
            ..|  ..||     :..|.|    ||...|.|..:..:.|:.:...|::|.|.|..:.::.||||
Zfish   157 MYR--HRKPPYGHVDVNEDP----GPSPPSPLVGLKPLQLLEVKARGRFGCVWKAQMINEYVAVK 215

  Fly   252 IYPEEHHQYYVNERNIYALPLMECPALLSYFGYDERCTMDGRMEYQLVLSLAPLGCLQDWLIANT 316
            |:|.:....:.|||.:::.|.|:...||.:...::|.: :..||:.|:......|.|.|:|..|.
Zfish   216 IFPIQDKLSWQNEREMFSTPGMKHDNLLRFIAAEKRGS-NLEMEFWLITEFHERGSLTDYLKGNA 279

  Fly   317 LTFSECCGMLRSITRGISHLHTEL--RLGDQHKPCVAHRDINTRNVLVQADLSCCIADFGFALKV 379
            :::::.|.:..|:..|:::||.::  ..|:..||.:||||..::||:::.||:..|.|||.|::.
Zfish   280 VSWADLCVIAESMACGLAYLHEDVPRSKGEGPKPAIAHRDFKSKNVMLKMDLTAVIGDFGLAVRF 344

  Fly   380 FGSKYEYKGEVAMAETKSINEVGTLRYMAPELLEGAVNL-RDCETSLKQMDVYALGLVLWEVATR 443
                     |.......:..:|||.||||||:||||:|. ||   |..::|:||:||||||:.:|
Zfish   345 ---------EPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRD---SFLRIDMYAMGLVLWELVSR 397

  Fly   444 CSDFYAPGQATPPYKAPYEQEVGSHPSFDQMQALVVRHKARPLFPTGWGGGAAAKVVRDTCEDCW 508
            |.....|   ...|..|:|:|:|.|||.:.:|..||..|.||.|...|...:....:.:|.|:||
Zfish   398 CKAADGP---VDEYMLPFEEEIGQHPSLEDLQDAVVHKKLRPAFKDCWLKHSGLCQMCETMEECW 459

  Fly   509 DHDADARLTSLCAEERMQEMSTLRPRAQAQPSSPLLN-----TNNLVASPTAEQGI 559
            ||||:|||::.|.:||:.::.    |..:..|..|.:     ||  |..|..|..|
Zfish   460 DHDAEARLSAGCVQERISQIR----RVSSSTSDCLFSMVTSLTN--VDLPPKESSI 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wit	NP_001261395.1	TFP_LU_ECD_Wit	25..138	CDD:467138	19/75 (25%)
		STKc_BMPR2_AMHR2	228..528	CDD:270956	107/302 (35%)
acvr2ba	NP_571285.1	TFP_LU_ECD_ACVR2B	26..116	CDD:467152	19/68 (28%)
		STKc_ACVR2b	192..482	CDD:271042	107/309 (35%)