Protein Alignment fus and esrp1

DIOPT Version :10

• Sequence 1: NP_524691.1
• Gene: fus / 44095
• FlyBaseID: FBgn0023441
• Length: 967
• Species: Drosophila melanogaster
• Sequence 2: NP_001005057.1
• Gene: esrp1 / 448608
• XenbaseID: XB-GENE-985138
• Length: 687
• Species: Xenopus tropicalis
• Alignment Length: 811
• Identity: 312/811 - (38%)
• Similarity: 412/811 - (50%)
• Gaps: 155/811 - (19%)

  Fly     4 PEHVVSLYIATCGQNGSGLGSDEKEIILLVFVLLEVSTGQIVGTKQILVRPDGYFIKDRTISSSS 68
            |:::|.|:..|.|.|||.|||||||:|.|::.::.::..::....::.||||       .:..:.
 Frog     6 PDYLVVLFTTTAGANGSKLGSDEKEVIQLLWKVINLANKKVGELHEVTVRPD-------HLELTE 63

  Fly    69 DNSSVTNNTASSPPLAIGDANNGSGSTSGNGNSLENGSELILPIAEAQAAGKPLSEAIEEFDAYL 133
            :...:|.                          :|..|..:.|         .|.:|:::|:..:
 Frog    64 ECKEITR--------------------------IEADSLYVAP---------QLEQALQQFNQSV 93

  Fly   134 -RSLSLH-DTEIKLVTDGQLPLRQCLHREASAKDVELPAYYNRFSDLRKEFLRYKSGDLARALVP 196
             ..|::. .|...:.|||||.:||.||.|||.|::.||..:..|.|||||||:...|.
 Frog    94 GNELNIGVGTSFCICTDGQLHIRQVLHPEASKKNILLPECFYSFFDLRKEFLKCCPGS------- 151

  Fly   197 VKDVKKMLQAPTLPMPQSIAEMLGELNISSVEDNDFY-IRESRDMVTVIQTLLQA--GHKFAANE 258
             .|..::          .:..|...|..........| ..|..||..:|.||:..  .:||:..|
 Frog   152 -SDTNEL----------DVHAMASYLGFEKKSTRYRYGASEVDDMGDIIVTLISEPYNYKFSDPE 205

  Fly   259 LVNLVLEPGICSIDDEVDGNCIVRARGLPWQSSDQDIAKFFRGLNVAKGGVALCLSPLGRRNGEA 323
            .||...|.|.||..:.:|.|.|:|||||||||||||||:||:|||:||||.||||:..|||||||
 Frog   206 RVNYKFESGTCSKLEIIDDNTIIRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEA 270

  Fly   324 LIRFVCQEHRDMALKRHKHHIGTRYIEVYRASGEDFLAIAGGASNEAQAFLSKGAQVIIRMRGLP 388
            |:|||.:||||:||:|||||:|.||||||:|:|||||.||||.|||...||||..|||:||||||
 Frog   271 LVRFVSEEHRDLALQRHKHHMGNRYIEVYKATGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLP 335

  Fly   389 YDATAKQVLDFFTTGDTPPCHVLDGNEGVLFVKKPDGRATGDAFVLFANETDAPKALGRHRESIG 453
            :.|||::||.||    ...|.|..|.||:|||..||.|.|||||||||.|..|..||.:|:|.:|
 Frog   336 FTATAEEVLAFF----GQQCPVTGGKEGILFVTYPDNRPTGDAFVLFACEEYAQNALKKHKELLG 396

  Fly   454 QRYIELFRSTTAEVQQVLNRSMDPKNYESGGGHSQPPLIAQLPTMQLPLLPQVGAHSLSHSLGAS 518
            :|||||||||.|||||||||            :|..||| .|||
 Frog   397 KRYIELFRSTAAEVQQVLNR------------YSSAPLI-PLPT--------------------- 427

  Fly   519 PANLCPPVPPPALPLPTQHLITSGTTKNCIRLRGLPYEAMVEHILHFLDDFAKHIIYQGVHMVIN 583
                     ||.:|:..|..|.....::|||||||||.|.:|.||.||.:|:..|...|||||:|
 Frog   428 ---------PPIIPVLPQPFIPPVNVRDCIRLRGLPYAATIEDILEFLGEFSADIRTHGVHMVLN 483

  Fly   584 AQGQPSGEAFIQMDLEESARLCAQRRHNHYMMFGKKYRYIEVFQCSGDDMNMVLNGGLASPVAQP 648
            .||:|||::||||...:.|.|.||:.|...|    |.||:||||||.::||.||.||..:.....
 Frog   484 HQGRPSGDSFIQMKSADRAYLAAQKCHKKTM----KDRYVEVFQCSAEEMNFVLMGGTLNRNGLS 544

  Fly   649 PPPHLGHAHKQQSLLAATTGMFSSAGQSPTTVAAGTAQSPLGGTHTHTHPHSHAHAHATGHAHAA 713
            |||     .|...|...:....:.|...||..||....|.|      .:|.|           ..
 Frog   545 PPP-----CKLPCLSPPSYTFPAQAAVIPTEAAALYQPSLL------LNPRS-----------LQ 587

  Fly   714 AAAAHHGLSAS-----SAMLPGLSAAASASGLASFMSAGQQSAAAAAHSAASLQNAAVALAP--- 770
            .:||::...|.     :|..|  |...|.|.|..|.::...|:....::.|.::...:|...
 Frog   588 PSAAYYPAGAQLFMNYTAYYP--SPPGSPSSLGFFPASASVSSIPPHNTGAMVRMQGLAYNSGVK 650

  Fly   771 ------QGYALNP-FSLPPPGSAAAAAASTP 794
                  |||..:| ..|.|....|.|..:.|
 Frog   651 EILNFFQGYQYSPEDGLLPVNDQARALLTHP 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fus	NP_524691.1	DnaQ_like_exo	13..194	CDD:447876	51/182 (28%)
		RRM1_Fusilli	280..359	CDD:241182	61/78 (78%)
		RRM2_Fusilli	363..462	CDD:410137	59/98 (60%)
		RRM3_Fusilli	545..629	CDD:241187	45/83 (54%)
esrp1	NP_001005057.1	DnaQ_like_exo	8..>146	CDD:447876	51/179 (28%)
		RRM1_ESRP1	217..309	CDD:410134	67/91 (74%)
		RRM2_ESRP1	311..421	CDD:410136	71/125 (57%)
		RRM3_ESRP1_ESRP2	445..525	CDD:410138	45/83 (54%)
		RRM_SF	636..>675	CDD:473069	8/38 (21%)