DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fus and Rbm12b

DIOPT Version :9

Sequence 1:	NP_524691.1	Gene:	fus / 44095	FlyBaseID:	FBgn0023441	Length:	967	Species:	Drosophila melanogaster
Sequence 2:	XP_006237956.2	Gene:	Rbm12b / 313069	RGDID:	1307658	Length:	843	Species:	Rattus norvegicus

Alignment Length:	415	Identity:	94/415 - (22%)
Similarity:	156/415 - (37%)	Gaps:	106/415 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   284 RGLPWQSSDQDIAKFFRGLNVAKGGVALCLSPLGRRNGEALIRFVCQEHRDMALKRHKHHIGTRY 348
            ||||:..::.|:..||.||.|  .||.|.....||.||:|:::|.........||.|:..:|:|:
  Rat   159 RGLPYLVNEDDVRVFFSGLCV--DGVILLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRF 221

  Fly   349 IEVYRASGEDFLAIAGGASNEAQAFLSKGAQ------------------------------VIIR 383
            |||.:.|.:.::...|.||........:..:                              ..:.
  Rat   222 IEVMQGSEQQWIEFGGTASKGGDTLHKRSEEHSPSRRLNDRYFWKRSRSKSPRTRSRSPLGFYVH 286

  Fly   384 MRGLPYDATAKQVLDFFTTGDTPPCHVLDGNEGVLFVKKPDGRATGDAFVLFANETDAPKALGRH 448
            :|.|......:.:...|...|.       .|:.:.|:.| |.|.|..|||:|.|:.|...|||.|
  Rat   287 LRNLSLHTNKRDLRYLFRDTDL-------SNDQIKFLYK-DDRRTRYAFVMFKNQKDYNTALGLH 343

  Fly   449 RESIGQRYIELFRSTTAEVQQVLNRSMDPKNYESGGGHSQPPLIAQLPTMQLPLLPQVGAHSLSH 513
            :..:..|.:.:...:..|:.::: ...:.|..||        |..:.|          |..|..:
  Rat   344 KTVLQYRPVLIDPISRKEMVKII-ECYEKKRPES--------LEEERP----------GRVSQKY 389

  Fly   514 SLGASPANLCPPVPPPALPLPTQHLITSGTTKNCIRLRGLPYEAMVEHILHFLDDFAKHIIYQGV 578
            |....|.                    || .|.||.:|.||::.....:..|..||:  ::...:
  Rat   390 SEEGFPG--------------------SG-QKLCIYIRNLPFDVTKGEVQKFFADFS--LVEDDI 431

  Fly   579 HMVINAQGQPSGEAFIQMDLEESA----RLCAQR-----------RHNHYMMFGKKYRYI---EV 625
            :::.:.:|...|||.::...||.|    ||..||           .......||..:.::   :.
  Rat   432 YLLSDDKGIGLGEALVRFKSEEQAMKAERLNRQRFLGTEVLLRLISEEQMQEFGVNFSWMSNEKT 496

  Fly   626 FQCS----GDDMNMVLNGGLASPVA 646
            ..||    |||.:.:.:  |..|:|
  Rat   497 QACSRSHDGDDCSCLFD--LKDPLA 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fus	NP_524691.1	DnaQ_like_exo	13..194	CDD:299142
		RRM1_Fusilli	280..359	CDD:241182	28/74 (38%)
		RRM2_Fusilli	363..462	CDD:241185	24/128 (19%)
		RRM3_Fusilli	545..629	CDD:241187	22/101 (22%)
Rbm12b	XP_006237956.2	RRM_SF	2..80	CDD:418427
		RRM2_RBM12B	152..237	CDD:410140	28/79 (35%)
		RRM_SF	283..362	CDD:418427	21/86 (24%)
		RRM	<367..581	CDD:223796	41/196 (21%)
		RRM4_RBM12B	401..476	CDD:410142	19/76 (25%)
		PTZ00465	<619..703	CDD:185644
		RRM_SF	767..843	CDD:418427
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349091
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840