DRSC/TRiP Functional Genomics Resources

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Protein Alignment fus and Rbm12b

DIOPT Version :10

Sequence 1:NP_524691.1 Gene:fus / 44095 FlyBaseID:FBgn0023441 Length:967 Species:Drosophila melanogaster
Sequence 2:NP_001395740.1 Gene:Rbm12b / 313069 RGDID:1307658 Length:843 Species:Rattus norvegicus


Alignment Length:415 Identity:94/415 - (22%)
Similarity:156/415 - (37%) Gaps:106/415 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   284 RGLPWQSSDQDIAKFFRGLNVAKGGVALCLSPLGRRNGEALIRFVCQEHRDMALKRHKHHIGTRY 348
            ||||:..::.|:..||.||.|  .||.|.....||.||:|:::|.........||.|:..:|:|:
  Rat   159 RGLPYLVNEDDVRVFFSGLCV--DGVILLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRF 221

  Fly   349 IEVYRASGEDFLAIAGGASNEAQAFLSKGAQ------------------------------VIIR 383
            |||.:.|.:.::...|.||........:..:                              ..:.
  Rat   222 IEVMQGSEQQWIEFGGTASKGGDTLHKRSEEHSPSRRLNDRYFWKRSRSKSPRTRSRSPLGFYVH 286

  Fly   384 MRGLPYDATAKQVLDFFTTGDTPPCHVLDGNEGVLFVKKPDGRATGDAFVLFANETDAPKALGRH 448
            :|.|......:.:...|...|.       .|:.:.|:.| |.|.|..|||:|.|:.|...|||.|
  Rat   287 LRNLSLHTNKRDLRYLFRDTDL-------SNDQIKFLYK-DDRRTRYAFVMFKNQKDYNTALGLH 343

  Fly   449 RESIGQRYIELFRSTTAEVQQVLNRSMDPKNYESGGGHSQPPLIAQLPTMQLPLLPQVGAHSLSH 513
            :..:..|.:.:...:..|:.::: ...:.|..||        |..:.|          |..|..:
  Rat   344 KTVLQYRPVLIDPISRKEMVKII-ECYEKKRPES--------LEEERP----------GRVSQKY 389

  Fly   514 SLGASPANLCPPVPPPALPLPTQHLITSGTTKNCIRLRGLPYEAMVEHILHFLDDFAKHIIYQGV 578
            |....|.                    || .|.||.:|.||::.....:..|..||:  ::...:
  Rat   390 SEEGFPG--------------------SG-QKLCIYIRNLPFDVTKGEVQKFFADFS--LVEDDI 431

  Fly   579 HMVINAQGQPSGEAFIQMDLEESA----RLCAQR-----------RHNHYMMFGKKYRYI---EV 625
            :::.:.:|...|||.::...||.|    ||..||           .......||..:.::   :.
  Rat   432 YLLSDDKGIGLGEALVRFKSEEQAMKAERLNRQRFLGTEVLLRLISEEQMQEFGVNFSWMSNEKT 496

  Fly   626 FQCS----GDDMNMVLNGGLASPVA 646
            ..||    |||.:.:.:  |..|:|
  Rat   497 QACSRSHDGDDCSCLFD--LKDPLA 519

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fusNP_524691.1 DnaQ_like_exo 13..194 CDD:447876
RRM1_Fusilli 280..359 CDD:241182 28/74 (38%)
RRM2_Fusilli 363..462 CDD:410137 24/128 (19%)
RRM3_Fusilli 545..629 CDD:241187 22/101 (22%)
Rbm12bNP_001395740.1 RRM_SF 2..80 CDD:473069
RRM2_RBM12B 152..237 CDD:410140 28/79 (35%)
RRM_SF 283..362 CDD:473069 21/86 (24%)
RRM4_RBM12B 401..476 CDD:410142 19/76 (25%)
PTZ00465 <619..703 CDD:185644
RRM_SF 767..843 CDD:473069
Blue background indicates that the domain is not in the aligned region.

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