DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fus and hrpf-1

DIOPT Version :9

Sequence 1:	NP_524691.1	Gene:	fus / 44095	FlyBaseID:	FBgn0023441	Length:	967	Species:	Drosophila melanogaster
Sequence 2:	NP_740877.1	Gene:	hrpf-1 / 172395	WormBaseID:	WBGene00020936	Length:	549	Species:	Caenorhabditis elegans

Alignment Length:	395	Identity:	96/395 - (24%)
Similarity:	150/395 - (37%)	Gaps:	128/395 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   382 IRMRGLPYDATAKQVLDFFTTGDTPPCHVLDGNEGV--LFVKKPDGRATGDAFVLFANETDAPKA 444
            ::.||||::||.:::.|||            ||.|:  |.:.:.:||.:|||.|:|.||.|...|
Worm     7 VQCRGLPWEATEQELRDFF------------GNNGIESLEIPRRNGRTSGDAKVVFTNEEDYNNA 59

  Fly   445 LGRHRESIGQRYIELF--------------RSTTAEVQQVLNRSMDPKNYES--GGGHSQPPLIA 493
            |.:.||.:|.||||:|              |....:.....:|...|::..|  ||..|..|
Worm    60 LKKDREHLGSRYIEVFPAGGAPTRRGDRGERGDRGDRDHYRSRGAPPRDRYSDRGGPRSSGP--- 121

  Fly   494 QLPTMQLPLLPQVGAHSLSHSLGASPANLCPPVPPPALPLPTQHLITSGTTKNCIRLRGLPYEAM 558
                                                               .:.:||||||:...
Worm   122 ---------------------------------------------------DSIVRLRGLPFSVT 135

  Fly   559 VEHILHFLDDFAKHIIYQGVHMVINAQGQPSGEAFIQMDLEESARLCAQRRHNHYMMFGKKYRYI 623
            ...|..||....  |:..|:.:....:.:|.|||::..:..||.::..||   |....|  :|||
Worm   136 SRDISDFLAPLP--IVRDGILLPDQQRARPGGEAYVCFETMESVQIAKQR---HMKNIG--HRYI 193

  Fly   624 EVFQCSGDDMN-MVLNGGLASPVAQPPPPHLGHAHKQQSLLAATTGMFSSAGQSPTTVAAGTAQS 687
            |||:.:..|:: ......|..|...|||                   |:||.|:          :
Worm   194 EVFEATHRDLSRFAEENDLRVPRFGPPP-------------------FASAPQT----------A 229

  Fly   688 PLGGTHTHTHPHSHAHAHATGHAHAAAAAAHHGLS-ASSAMLPGLSAA-----ASASGLASFMSA 746
            |.|....::.| :..:.:||.:..||.....:..| |.|....|:.|:     ..|:.::|:.|.
Worm   230 PRGAYDPYSQP-TDPYRNATDYRRAAEPEDPYARSRAPSVQDYGVRASYDPYTQPAAPVSSYPSQ 293

  Fly   747 GQQSA 751
            .|.||
Worm   294 QQPSA 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fus	NP_524691.1	DnaQ_like_exo	13..194	CDD:299142
		RRM1_Fusilli	280..359	CDD:241182
		RRM2_Fusilli	363..462	CDD:241185	33/95 (35%)
		RRM3_Fusilli	545..629	CDD:241187	27/83 (33%)
hrpf-1	NP_740877.1	RRM_hnRNPH_ESRPs_RBM12_like	7..75	CDD:240700	32/79 (41%)
		RRM	<10..183	CDD:223796	58/240 (24%)
		RRM	<98..313	CDD:223796	62/292 (21%)
		RRM_SF	123..199	CDD:302621	27/82 (33%)
		RRM_hnRNPH_ESRPs_RBM12_like	472..542	CDD:240700
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910