DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fus and grsf1

DIOPT Version :9

Sequence 1:	NP_524691.1	Gene:	fus / 44095	FlyBaseID:	FBgn0023441	Length:	967	Species:	Drosophila melanogaster
Sequence 2:	XP_031748425.1	Gene:	grsf1 / 100337653	XenbaseID:	XB-GENE-965150	Length:	440	Species:	Xenopus tropicalis

Alignment Length:	451	Identity:	105/451 - (23%)
Similarity:	176/451 - (39%)	Gaps:	132/451 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   249 QAGHKFAANELVNLVLEPGICSIDDEVDGN------------------------CIVRARGLPWQ 289
            |||.:::..:.....||...|| ...:||:                        .|||.|||||.
Frog    41 QAGREWSRVQEYRRRLERSYCS-GQNIDGSFQKDWYPPLPEYDPQPLANKLTTMFIVRVRGLPWS 104

  Fly   290 SSDQDIAKFFRGLNVAKG--GVALCLSPLGRRNGEALIRFVCQEHRDMALKRHKHHIGTRYIEVY 352
            .:..|:..||...||..|  ||....:..|:..|:|:|.|...|....|:::||.::|.||:||:
Frog   105 CTADDVLNFFGDSNVRNGTEGVHFIFNRDGKPRGDAVIEFESAEDVQKAVEQHKKYMGQRYVEVF 169

  Fly   353 RASGEDFLAIAGGASNEAQAFL------------------------SKGAQVIIRMRGLPYDATA 393
            ..:           ..||::.|                        |..:..::|:|||||..:.
Frog   170 EMN-----------QKEAESLLNRMHSALSPTRPSSMSLSPQSSMASPPSDGVVRLRGLPYSCSE 223

  Fly   394 KQVLDFFTTGDTPPCHVLDGNEGVLFVKKPDGRATGDAFVLFANETDAPKALGRHRESIGQRYIE 458
            :.::.||:..|.       .:||:.||....||.:|:|||.|.::..|.:||.:|::.||.||||
Frog   224 QDIIHFFSGLDI-------ADEGITFVLDQRGRKSGEAFVQFLSQEHADQALLKHKQEIGSRYIE 281

  Fly   459 LFRSTTAEVQ---------------QVLNRSMDPKNYESGGGHSQPPLIAQLPTMQLPLLPQVGA 508
            :|.|...|:|               ..:....||.|..:   ::...|::.:|.         ..
Frog   282 IFPSRRNEIQTARFPFRRRKGVTFAPTIKDLYDPDNCIN---NTSKDLLSDVPE---------NG 334

  Fly   509 H-------SLSHSLGASPANLCPPVPPPALPLPTQHLITSGTTKNCIRLRGLPYEAMVEHILHFL 566
            |       ..:.|:......:..||                   :.|.:||||:.|..:.|.:|.
Frog   335 HINDYVKEMSAKSMDVQDFTVMSPV-------------------HDIHIRGLPFHASGQDIANFF 380

  Fly   567 DDFAKHIIYQGVHMVINAQ-GQPSGEAFIQMDLEESARLCAQRRHNHYMMFGKKYRYIEVF 626
            ..    |:...:.:..:|. |..:|||.::....|.|.....:...|     .::.|:|::
Frog   381 HP----IMPLKISIEYSADAGGATGEAVVRFLTHEDAVAAMAKNRCH-----TQHGYLELY 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fus	NP_524691.1	DnaQ_like_exo	13..194	CDD:299142
		RRM1_Fusilli	280..359	CDD:241182	30/80 (38%)
		RRM2_Fusilli	363..462	CDD:241185	35/122 (29%)
		RRM3_Fusilli	545..629	CDD:241187	19/83 (23%)
grsf1	XP_031748425.1	RRM1_GRSF1	93..171	CDD:410129	30/77 (39%)
		RRM2_GRSF1	209..286	CDD:409928	31/83 (37%)
		RRM3_GRSF1	360..435	CDD:410132	19/82 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D392876at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920