Protein Alignment Rs1 and ddx27

DIOPT Version :10

• Sequence 1: NP_651970.1
• Gene: Rs1 / 44087
• FlyBaseID: FBgn0021995
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_001002869.1
• Gene: ddx27 / 378844
• ZFINID: ZDB-GENE-031001-8
• Length: 776
• Species: Danio rerio
• Alignment Length: 825
• Identity: 374/825 - (45%)
• Similarity: 508/825 - (61%)
• Gaps: 115/825 - (13%)

  Fly     7 LDLIGTIEDDAEV-ENLSEDSDAEVEYQPTKLRHKKVT--------EFEKGFEFVSSVKEYNQDT 62
            :|||.||:||.|| |.....||.|.: ||..|:.|:..        .|...|:|......|:.|
Zfish     1 MDLIRTIDDDEEVPEEPDSGSDDEAD-QPIVLKSKEKQALKARGSGHFNADFDFGERDGLYSAD- 63

  Fly    63 W---DDLMKYVKRKARTKTDDKIAARLQKRGGAEAVAAEQSDGSEIDLSEDELKHDNLRLREKKE 124
            |   |.:.:..||||.|..|:|| .:::|:...|..:.:::..:|...|:   |||:....|::|
Zfish    64 WAMADVMAQLKKRKAPTTLDEKI-EKVRKKRKVEEKSQKENKKTETSASK---KHDDQEEEEEEE 124

  Fly   125 SKKKKKK---------------AGEEDEEDEGE----------------------KMQFADTVEA 152
            ...::::               .|::|::||.|                      |.:.|||.|.
Zfish   125 EDDEEEEEDNDADDNDADEVSGGGDDDDDDEDEFSSADEEVLKKADTLREKQKKGKRKMADTTEG 189

  Fly   153 --------NEQITSFYQMNLSRPLMRAIGVLGYIYPTPIQASTIPVALLGRDICGCAATGTGKTA 209
                    :|.:| |:.|||||||::||..:|:..|||||.:.:||.|||:|||.||||||||||
Zfish   190 FFEDASQYDENLT-FHDMNLSRPLLKAISTMGFKQPTPIQKACVPVGLLGKDICACAATGTGKTA 253

  Fly   210 AYMLPTLERLLYRPLNNKAITRVLVLVPTRELGAQVYQVTKQLCQFTTIDVGLAIGGLDVKAQEA 274
            |:|||.||||:|:|...: :|||||||||||||.||:.|.:||.|||||...||:||||:|:|||
Zfish   254 AFMLPVLERLIYKPRETQ-VTRVLVLVPTRELGIQVHTVARQLAQFTTISTCLAVGGLDLKSQEA 317

  Fly   275 VLRQNPDIVIATPGRLIDHIKNTPSFTLDSIEVLILDEADRMLDEYFAEQMKEIINSCCKTRQTM 339
            .||..||::||||||||||:.|||||.|..||:||||||||||||||.|||||||..|...||||
Zfish   318 ALRAGPDVLIATPGRLIDHLHNTPSFELSQIEILILDEADRMLDEYFEEQMKEIIRMCAYQRQTM 382

  Fly   340 LFSATMSEQVKDLAAVSLDKPIKVFVNNNQQVAFNLRQEFIRIREDKEGDREPILASLICRTFHD 404
            ||||||||:|||||:|||.:|:::|||:|..||..|||||:|||.:||||||.|:|:|:.|||.|
Zfish   383 LFSATMSEEVKDLASVSLKQPVRIFVNSNTDVAPYLRQEFVRIRPNKEGDREAIVAALLTRTFQD 447

  Fly   405 HCMVFVQTKKQAHRLHILLGLLGVRAGELHGNLTQQQRLESLKKFKEEQIDVLIATDVAARGLDI 469
            |.|:|.||||||||:||||||:|::.|||||||:|.||||||::||:||||:|:|||||||||||
Zfish   448 HVMLFTQTKKQAHRMHILLGLMGLKVGELHGNLSQTQRLESLRRFKDEQIDILVATDVAARGLDI 512

  Fly   470 VGVKTVINFVMPITTEHYIHRVGRTARAGRAGISVSLAGEKERKIVKDIIKNAESTIKNRIIPPE 534
            .||||||||.||.|.:||:||||||||||:.|.||||.||.|||::|:|:|.|:..:|.|:||.|
Zfish   513 EGVKTVINFTMPNTVKHYVHRVGRTARAGKVGRSVSLVGETERKMLKEIVKKAKFPVKARVIPQE 577

  Fly   535 IIEKYRNKLTSLEPEIQNILDEEQAERQLAKTEQQLSKTERKLLGQTNER---RGWFQTKQQREA 596
            :|.|:|:.:..||.::..:|..|:.|:::|.:|.|:|..:::|....:|:   |.||||.::|
Zfish   578 VILKFRDLIEKLEKDVYAVLCLEKEEKEMAHSEAQISSAQKRLTKSEDEKQLPRTWFQTNEER-- 640

  Fly   597 EKDRLALTTGDEDKASGGKGKGKTAGKRKRPEYGGDGEDGPPVKDLEAKRNKKKKEEPRKKTPEQ 661
            :|||:|....|.|.|        ..||:||.::              .|:.|:|         |.
Zfish   641 KKDRMAKALQDFDLA--------LRGKKKRAQF--------------LKQGKRK---------EL 674

  Fly   662 LAKERAMKEIEKVSLVRAKMAKLRKRPGKLGAATEVHRSGASDGKPKRR-----GGQSAFTNDLT 721
            .|:|||..|:.|..:...:.||..::..:..|..|    ...|.|..::     |.:|.|..:||
Zfish   675 TAEERAQLEVLKSQMFAERAAKRERKQKRARAIPE----DQPDKKALKKNAGKAGKKSVFDKELT 735

  Fly   722 DVSRGGALRLRSEANRHKKMTKIAAKKKASSVKLTNKAGKNKFNK 766
            :.|:....:.|:..:...:.......||....|     .|.||.:
Zfish   736 NTSKKNLKQYRAGPSFEDRKRLGLPNKKGGRFK-----SKAKFKR 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rs1	NP_651970.1	SrmB	156..576	CDD:440279	274/419 (65%)
ddx27	NP_001002869.1	SrmB	202..591	CDD:440279	266/390 (68%)