Protein Alignment Rs1 and pths

DIOPT Version :10

• Sequence 1: NP_651970.1
• Gene: Rs1 / 44087
• FlyBaseID: FBgn0021995
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: XP_318913.5
• Gene: pths / 1279222
• VectorBaseID: AGAMI1_006527
• Length: 507
• Species: Anopheles gambiae
• Alignment Length: 547
• Identity: 180/547 - (32%)
• Similarity: 278/547 - (50%)
• Gaps: 57/547 - (10%)

  Fly    95 VAAEQSDGSEIDLSEDELKHDNLRLREKKESKKKKKKAGEEDEEDEGEKMQFADTVEANEQITSF 159
            :::.:|||.. |:.|......|   .:....:::.....:.|||.:|:..:..|..:      |:
Mosquito     1 MSSSESDGMS-DVEEAARAAAN---GDDSSDQEENGSGTDGDEEQDGQAEKGTDVSK------SW 55

  Fly   160 YQMNLSRPLMRAIGVLGYIYPTPIQASTIPVALLGRDICGCAATGTGKTAAYMLPTLERLLYRPL 224
            ..:.|...|..|...|.:..|:.||...||:||.|:||.|.|.||:|||.|:.||.|:.||..|.
Mosquito    56 EDLGLIDTLCTACRGLKWKAPSKIQREAIPLALQGKDIIGLAETGSGKTGAFALPILQALLDNPQ 120

  Fly   225 NNKAITRVLVLVPTRELGAQVYQVTKQL-CQFTTIDVG--LAIGGLDVKAQEAVLRQNPDIVIAT 286
            ...|:    ||.|||||   .||:::|. ....||.|.  :.:||:|:..|...|.:.|.|:|||
Mosquito   121 RYFAV----VLTPTREL---AYQISEQFEALGATIGVKCCVIVGGMDLVTQAIQLARKPHIIIAT 178

  Fly   287 PGRLIDHIKNTPSFTLDSIEVLILDEADRMLDEYFAEQMKEIINSCCKTRQTMLFSATMSEQVKD 351
            ||||:||::||..|:|.:|..|::|||||:|:..|.|::.:|:....:.|:|.||||||:::||.
Mosquito   179 PGRLVDHLENTKGFSLKAIRYLVMDEADRILNMDFEEEVNKILKVMPRERRTFLFSATMTKKVKK 243

  Fly   352 LAAVSLDKPIKVFVNNNQQVAFNLRQEFIRI-REDKEGDREPILASLICRTFHDHCMVFVQTKKQ 415
            |...||..|:||.|::..|....|.|.::.| ...|......:|..|...:|    |:|..|...
Mosquito   244 LERASLRDPVKVEVSSKYQTVEKLLQYYLFIPARYKNVYLVHVLNELAGNSF----MIFCSTCNN 304

  Fly   416 AHRLHILLGLLGVRAGELHGNLTQQQRLESLKKFKEEQIDVLIATDVAARGLDIVGVKTVINFVM 480
            ..|..::|..||:.|..|||.:||.:||.:|.|||.:...:||:||||:|||||..|..|:|..:
Mosquito   305 TVRTALMLRALGLAAVPLHGQMTQNKRLAALNKFKSQARQILISTDVASRGLDIPHVDVVLNLDI 369

  Fly   481 PITTEHYIHRVGRTARAGRAGISVSLAGEKERKIVKDIIKNAESTIKNRIIPPEIIEKYRNKLTS 545
            |:.::.|||||||||||||||.:::...:.:                     .|:.::..:.|..
Mosquito   370 PMHSKDYIHRVGRTARAGRAGQAITFVTQYD---------------------VELYQRIEHLLGK 413

  Fly   546 LEPEIQNILDEEQAERQLAKTEQQLSKTERKLLGQTNERRGWFQTKQQREAE--------KDRLA 602
            ..||.:...||..|.::......:.::.|::.:.:....:|..:.....:.|        :.||.
Mosquito   414 KLPEYKCEQDEVMALQERVAEAHRTARIEQRDIEERKASKGGKRGANDSDEEDTEQFNGVRKRLK 478

  Fly   603 ---LTTGDEDKASGGKGKGKTAGKRKR 626
               ...||.....|..|:|...|||.|
Mosquito   479 PGNAKGGDRGGRGGRGGRGGRGGKRGR 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rs1	NP_651970.1	SrmB	156..576	CDD:440279	156/423 (37%)
pths	XP_318913.5	None