Protein Alignment Rs1 and Dbp45A

DIOPT Version :10

• Sequence 1: NP_651970.1
• Gene: Rs1 / 44087
• FlyBaseID: FBgn0021995
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: XP_314012.3
• Gene: Dbp45A / 1274808
• VectorBaseID: AGAMI1_014202
• Length: 531
• Species: Anopheles gambiae
• Alignment Length: 582
• Identity: 177/582 - (30%)
• Similarity: 255/582 - (43%)
• Gaps: 116/582 - (19%)

  Fly   159 FYQMNLSRPLMRAIGVLGYIYPTPIQASTIPVALLGRDICGCAATGTGKTAAYMLPTLERLLYRP 223
            |..:.|:..:.|....||...|||||...||..|.|:|..|.|.||:|||.|:.||.|::|...|
Mosquito     9 FSDLGLTYWITRQTEKLGLRRPTPIQVECIPRILQGQDCIGAAKTGSGKTFAFALPILQKLSEEP 73

  Fly   224 LNNKAITRVLVLVPTRELGAQVYQ--------VTKQLCQFTTIDVGLAIGGLDVKAQEAVLRQNP 280
            ..|.|    |||.||.||..|:.:        :..::|..|        ||.|...:...|.:.|
Mosquito    74 TANFA----LVLTPTHELAHQIAEQFIVAGQPMNARVCVVT--------GGTDYLIESQQLEKRP 126

  Fly   281 DIVIATPGRLIDHIKNTPSFTLDSIEVLILDEADRMLDEYFAEQMKEIINSCCKTRQTMLFSATM 345
            .|::|.||||.||:....:::..:::.|::|||||||...|.|.:..|.......||.:.||||:
Mosquito   127 HIIVAMPGRLADHLTGCNTYSFAALQFLVVDEADRMLCGSFDEDLMVINRFLPAKRQNLFFSATL 191

  Fly   346 SEQVKDLAAVSLDKPI--KVFVNNNQQ---VAFNLRQEFIRIREDKEGDREPILASLICRTFHDH 405
                ||....|:..||  .||..:.|.   ....|.|.::..   .:.||:.::...:.:...|.
Mosquito   192 ----KDFLKTSIVFPIADDVFEWSEQSPVATVETLDQRYLLC---ADYDRDTVMVEALRKYKEDQ 249

  Fly   406 ----CMVFVQTKKQAHRLHILLGLLGVRAGELHGNLTQQQRLESLKKFKEEQIDVLIATDVAARG 466
                .|:|..:||....|.:.|...|.....|||.|.|::|:.:|.|||.:.:.::||||||:||
Mosquito   250 EDASIMIFTNSKKDCQILSMSLNSFGFSNVCLHGFLRQRERVAALNKFKSKHVRIMIATDVASRG 314

  Fly   467 LDIVGVKTVINFVMPITTEHYIHRVGRTARAGRAGISVSL---------AGEKERKI-------- 514
            |||..|:.|:|..:|.....|||||||||||||||:::|:         .||.|..|
Mosquito   315 LDIHDVQLVVNHRLPKKPIEYIHRVGRTARAGRAGMAISILRFPRDLEALGEIEALINTKLTEYS 379

  Fly   515 ------------VKDIIKNAESTIKNRIIPPEIIEKYRNKLTSLEPEIQNILDEEQAERQLAKTE 567
                        ||.....||..:.|:.. .|...|||....     ||..||.::.|.:..:..
Mosquito   380 VDDRLVQRIFMQVKVARAEAEINLDNKDF-DERKHKYRRLRW-----IQEGLDPDEMEAKWKEDM 438

  Fly   568 QQLSKTERKLLGQTNERRGWFQTKQQREAEKDRLALTTGDEDKASGGKGKGKTAGKRKRPEYGGD 632
            :...:..|:.|.|.||.|        |:.:|..:|                       .|....|
Mosquito   439 KAREQERRERLRQENEER--------RKRDKQTIA-----------------------SPAVVND 472

  Fly   633 GEDGPPVKDLEAKRNKKKKEEPRKKTPEQL----------AKERAM-KEIEKVSLVRAKMAK 683
            ........|   |:.||:|..|.:|..|.:          .|.||. |..:|:...:||||:
Mosquito   473 ARFQAAASD---KKFKKRKFIPTEKLNELIEQRKTEAKGGKKARARGKGDKKIVKKKAKMAQ 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rs1	NP_651970.1	SrmB	156..576	CDD:440279	149/462 (32%)
Dbp45A	XP_314012.3	SrmB	8..382	CDD:440279	135/391 (35%)