| Sequence 1: | NP_001138594.1 | Gene: | CAPN14 / 440854 | HGNCID: | 16664 | Length: | 684 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_031627.2 | Gene: | Capn3 / 12335 | MGIID: | 107437 | Length: | 821 | Species: | Mus musculus |
| Alignment Length: | 772 | Identity: | 278/772 - (36%) |
|---|---|---|---|
| Similarity: | 395/772 - (51%) | Gaps: | 122/772 - (15%) |
- Green bases have known domain annotations that are detailed below.
|
Human 27 QQDFEALLAECLRNGCLFEDTSFPATLSSIGSGSLLQKLPPRLQWKRPPELHSNPQFYFAKAKRL 91
Human 92 DLCQGIVGDCWFLAALQALALHQDILSRVVPLNQSFTEKYAGIFRFWFWHYGNWVPVVIDDRLPV 156
Human 157 NEAGQLVFVSSTYKNLFWGALLEKAYAKLSGSYEDLQSGQVSEALVDFTGGVTMTINLAEAHGNL 221
Human 222 WDILIEATYNRTLIGCQTHSGEKI---------------------LEN----------------- 248
Human 249 ---------------GLVEGHAYTLTGIRKVTCKHRPEYLVKLRNPWGKVEWKGDWSDSSSKWEL 298
Human 299 LSPKEKILLLRK-DNDGEFWMTLQDFKTHFVLLVICKLTPGLLSQEAAQKWTYTMREGRWEKRST 362
Human 363 AGGQRQLLQDTFWKNPQFLLSVWR----PEEGRRSLRPCSVLVSLLQKPRHRCRK-RKPLLAIGF 422
Human 423 YLYRMNK-YHDDQRRLPPEFFQRNTPLSQPDRFLKEKEVSQELCLEPGTYLIVPCILEAHQKSEF 486
Human 487 VLRVFSRKHIFYEIGSNS-------------GVVF-------SKEI------------------- 512
Human 513 ----------EDQNERQDEF---FTKFFEKHPEINAVQLQNLLNQMTWSSLGSRQPFFSLEACQG 564
Human 565 ILALLDLNASGTMSIQEFRDLWKQLKLSQKVF-HKQDRGSGYLNWEQLHAAMREAGIMLSDDVCQ 628
Human 629 LMLIRYGGPRLQMDFVSFIHLMLRVENMEDVFQNLTQDGKGIY-LQKPEWMMMALYS 684 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CAPN14 | NP_001138594.1 | Peptidase_C2 | 44..334 | CDD:279042 | 142/343 (41%) |
| Domain III | 337..503 | 66/171 (39%) | |||
| Calpain_III | 348..496 | CDD:279416 | 63/153 (41%) | ||
| Linker | 504..517 | 3/61 (5%) | |||
| Domain IV | 518..683 | 55/169 (33%) | |||
| EFh | 562..616 | CDD:298682 | 21/54 (39%) | ||
| Capn3 | NP_031627.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..37 | ||
| Peptidase_C2 | 77..415 | CDD:279042 | 142/341 (42%) | ||
| Domain III | 418..586 | 66/171 (39%) | |||
| Calpain_III | 429..579 | CDD:279416 | 63/153 (41%) | ||
| Calpain_u2 | 583..653 | CDD:293254 | 6/69 (9%) | ||
| Linker | 587..649 | 3/61 (5%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 603..651 | 4/47 (9%) | |||
| Domain IV | 650..820 | 55/169 (33%) | |||
| EFh | 653..722 | CDD:238008 | 22/68 (32%) | ||
| EFh | 697..751 | CDD:238008 | 20/53 (38%) | ||
| EFh | 728..817 | CDD:298682 | 29/88 (33%) | ||
| EF-hand_7 | 728..784 | CDD:290234 | 17/55 (31%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG0045 | |
| HGNC | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| NCBI | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D704215at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000071 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X74 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 6 | 5.820 | |||||