DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ag5r2 and Clec18a

DIOPT Version :9

Sequence 1:	NP_524689.2	Gene:	Ag5r2 / 44079	FlyBaseID:	FBgn0020508	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_030099497.1	Gene:	Clec18a / 353287	MGIID:	2672935	Length:	615	Species:	Mus musculus

Alignment Length:	269	Identity:	49/269 - (18%)
Similarity:	86/269 - (31%)	Gaps:	85/269 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LAILIVSLALAQATDYCSSDICNGGSHIACGHSNWWDSSCP---GDAELIDINDDYKWVFVHSHN 67
            |.:|::.|:|...|                    |.:...|   .|..|..::....::.:.:||
Mouse    91 LGLLLLLLSLLGIT--------------------WTEVQPPQPKQDPTLQALSRKESFLILTAHN 135

  Fly    68 DKRNYIAGGYDSNHNAACRMATMEWDDELAYLASLNVRQC------NMVHDSCHNTDAFKYSGQN 126
            ..|:.:       |..|..|..|:|.:.||.||......|      |:.....||:        :
Mouse   136 RLRSRV-------HPPAANMQRMDWSESLAQLAEARAALCVTSVTPNLASTPGHNS--------H 185

  Fly   127 LAWQAYSGDLPDMGYILDNSVQMWFDE-----------VHNSNAGIIAGGYPSGYNGPAIGHFTV 180
            :.|......:....::  ..|.:||.|           .||:..                .|:|.
Mouse   186 VGWNVQLMPMGSASFV--EVVNLWFAEGLQYRHGDAECAHNATC----------------AHYTQ 232

  Fly   181 MMSERNTRLGCAAARYNRDGWNQVLVACNYA---TTNMIGRQI--YSSCDWGAQGCGSGTNGEF- 239
            ::...:::|||.......|........|.|:   ..::.|:.:  |....| ...|.:..:|.|
Mouse   233 LVWATSSQLGCGRQPCFVDQEAMEAFVCAYSPGGNWDINGKTVAPYKKGTW-CSLCTARVSGCFK 296

  Fly   240 -----GNLC 243
                 |.||
Mouse   297 AWDHAGGLC 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ag5r2	NP_524689.2	SCP_euk	62..211	CDD:240180	30/165 (18%)
Clec18a	XP_030099497.1	CAP_euk	129..263	CDD:349399	30/166 (18%)
		EGF_Lam	315..360	CDD:214543
		CLECT	390..514	CDD:153057
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841145
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850