DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ag5r2 and Crispld1

DIOPT Version :9

Sequence 1:	NP_524689.2	Gene:	Ag5r2 / 44079	FlyBaseID:	FBgn0020508	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001128435.1	Gene:	Crispld1 / 316482	RGDID:	1564813	Length:	500	Species:	Rattus norvegicus

Alignment Length:	289	Identity:	71/289 - (24%)
Similarity:	103/289 - (35%)	Gaps:	90/289 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LALLAILIV-----SLALAQAT-------DYCSSDICNGGSHIACGHSNWWDSSCPGDAELIDIN 55
            |.:.|:|.|     ::.:..||       .|...|            ..||.:...|...:.| |
  Rat     9 LRMTALLFVARAVPAMVVPNATLLEKLLEKYMDED------------DEWWTAKQRGKRAITD-N 60

  Fly    56 DDYKWVFVHSHNDKRNYIAGGYDSNHNAACRMATMEWDDELAYLASLNVRQCNMVHDSCHNTDAF 120
            |...  .:..||..|:.:       :.||..|..|.||.||...|......|...|..   |...
  Rat    61 DMQS--ILDLHNKLRSQV-------YPAASNMEYMTWDVELERSAESWAETCLWEHGP---TSLL 113

  Fly   121 KYSGQNLA--WQAYSGDLPDMGYILDNSVQMWFDEVHNSNAGIIAGGYPSGY----------NGP 173
            ...||||.  |..|.   |...:     ||.|:|||.:.:       ||..:          :||
  Rat   114 PSIGQNLGAHWGRYR---PPTFH-----VQAWYDEVRDFS-------YPYEHECDPYCPFRCSGP 163

  Fly   174 AIGHFTVMMSERNTRLGCAA-ARYNRDGWNQ-----VLVACNYATT-NMIGRQIY------SSC- 224
            ...|:|.::...::|:|||. ..:|.:.|.|     |.:.|||:.. |..|...|      |:|
  Rat   164 VCTHYTQVVWATSSRIGCAINLCHNMNIWGQIWPKAVYLVCNYSPKGNWWGHAPYKHGKPCSACP 228

  Fly   225 -DWGAQGCGSGTNGEFGNLC---STSEWY 249
             .:|. ||..       |||   .:.::|
  Rat   229 PSFGG-GCRE-------NLCYKEGSDQYY 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ag5r2	NP_524689.2	SCP_euk	62..211	CDD:240180	44/166 (27%)
Crispld1	NP_001128435.1	SCP_euk	63..207	CDD:240180	44/170 (26%)
		LCCL	291..375	CDD:128866
		LCCL	394..492	CDD:281766
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344620
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850