DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ag5r2 and vap-2

DIOPT Version :9

Sequence 1:	NP_524689.2	Gene:	Ag5r2 / 44079	FlyBaseID:	FBgn0020508	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001300377.1	Gene:	vap-2 / 181273	WormBaseID:	WBGene00011462	Length:	507	Species:	Caenorhabditis elegans

Alignment Length:	251	Identity:	65/251 - (25%)
Similarity:	99/251 - (39%)	Gaps:	41/251 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 IVSLALAQATDYCSSDICNGGSHIACGHSNWWDSSCPGDAELIDINDDYKWVFVHSHNDKRNYIA 74
            :|...|.||......|   ||| ..|.:|.              ::|..:...:..||..|:.:|
Worm   285 LVPEGLCQAPSMVKDD---GGS-FQCDNSL--------------VSDVTRNFTLEQHNFYRSRLA 331

  Fly    75 GGYDSNHNA------ACRMATMEWDDELAYLASLNVRQCNMVHDSCHNTDAFKYSGQNLAWQAYS 133
            .|::.|...      |.:|..||:|..|...|......|...|.:.:..   ...||||...::|
Worm   332 KGFEWNGETNTSQPKASQMIKMEYDCMLERFAQNWANNCVFAHSAHYER---PNQGQNLYMSSFS 393

  Fly   134 GDLPDMGYILDNSVQMWFDEVHNSNAGIIAGGYPSGYN--GPAIGHFTVMMSERNTRLGCAAARY 196
            .  ||...::..:|:.|:.|:......|.....|..::  |.||||:|.|..:|..||||..|..
Worm   394 N--PDPRSLIHTAVEKWWQELEEFGTPIDNVLTPELWDLKGKAIGHYTQMAWDRTYRLGCGIANC 456

  Fly   197 NRDGWNQVLVACNYATT-NMIGRQIY---SSCDWGAQGCGSGTNGE-FGNLCSTSE 247
            .:..:    |.|:|... |....:||   ..|:.. ..|..||:.| ..:||..|:
Worm   457 PKMSY----VVCHYGPAGNRKNNKIYEIGDPCEVD-DDCPIGTDCEKTTSLCVISK 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ag5r2	NP_524689.2	SCP_euk	62..211	CDD:240180	42/156 (27%)
vap-2	NP_001300377.1	SCP	104..253	CDD:214553
vap-2	NP_001300377.1	SCP	315..468	CDD:214553	43/161 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920