DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ag5r2 and GLIPR1L2

DIOPT Version :9

Sequence 1:	NP_524689.2	Gene:	Ag5r2 / 44079	FlyBaseID:	FBgn0020508	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001257325.1	Gene:	GLIPR1L2 / 144321	HGNCID:	28592	Length:	344	Species:	Homo sapiens

Alignment Length:	231	Identity:	50/231 - (21%)
Similarity:	87/231 - (37%)	Gaps:	68/231 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 DAELIDINDDYKWVFVHSHNDKR-NYIAGGYDSNHNAACRMATMEWDDELAYLASLNVRQC---- 107
            |.|.:|..::|    |:.||:.| :.|..|  ||      :..|.||..|:..|....::|
Human    47 DEEDVDFINEY----VNLHNELRGDVIPRG--SN------LRFMTWDVALSRTARAWGKKCLFTH 99

  Fly   108 -------NMVHDSCHNTDAFKYSGQNLAWQAYSGDLPDMGYILDNSVQMWFDE--VHNSNAGIIA 163
                   .|||..      |...|:|: |..     |:..:....:::.|..|  ::|...|..:
Human   100 NIYLQDVQMVHPK------FYGIGENM-WVG-----PENEFTASIAIRSWHAEKKMYNFENGSCS 152

  Fly   164 GGYPSGYNGPAIGHFTVMMSERNTRLGCAAARYNRDGW--NQVLVACNYATTNMIGRQIYSS--- 223
            |.         ..::..::.:.:.::|||....::.|.  :..:..||||....:.|:.|..
Human   153 GD---------CSNYIQLVWDHSYKVGCAVTPCSKIGHIIHAAIFICNYAPGGTLTRRPYEPGIF 208

  Fly   224 CDWGAQGCGSGTN-GEFGNLCSTSE---------WY 249
            |    ..||.... .:|  |||.::         ||
Human   209 C----TRCGRRDKCTDF--LCSNADRDQATYYRFWY 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ag5r2	NP_524689.2	SCP_euk	62..211	CDD:240180	33/164 (20%)
GLIPR1L2	NP_001257325.1	SCP_GLIPR-1_like	52..195	CDD:240185	37/175 (21%)
GLIPR1L2	NP_001257325.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..344
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151314
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750