Protein Alignment Ag5r2 and CRISP3

DIOPT Version :10

• Sequence 1: NP_524689.2
• Gene: Ag5r2 / 44079
• FlyBaseID: FBgn0020508
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_001355052.1
• Gene: CRISP3 / 10321
• HGNCID: 16904
• Length: 276
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 57/272 - (20%)
• Similarity: 94/272 - (34%)
• Gaps: 61/272 - (22%)

  Fly     8 ILIVSLALAQATDYCSSDICNGG------------SHIACG-----HSNWWDSSCPGDAELIDIN 55
            ||..:|.....|::.::|.|:.|            ..:..|     .:|  :...|....|:...
Human     4 ILHPALETTACTNHFNADPCSTGFVFPAMTLFPVLLFLVAGLLPSFPAN--EDKDPAFTALLTTQ 66

  Fly    56 DDYKWVFVHSHNDKRNYIAGGYDSNHNAACRMATMEWDDELAYLASLNVRQCNMVHDSCHNTDAF 120
            ...:...|:.||:.|..::       ..|..|..|||:.|.|..|.....|||..|.:..:....
Human    67 TQVQREIVNKHNELRRAVS-------PPARNMLKMEWNKEAAANAQKWANQCNYRHSNPKDRMTS 124

  Fly   121 KYSGQNLAWQAYSGDLPDMGYILDNSVQMWFDEVHNSNAGIIAGGYPSGYNGP-----AIGHFTV 180
            ...|:||...:.|..       ...::|.||||.::.:.|:          ||     .:||:|.
Human   125 LKCGENLYMSSASSS-------WSQAIQSWFDEYNDFDFGV----------GPKTPNAVVGHYTQ 172

  Fly   181 MMSERNTRLGCAAARYNRDGWNQVLVACNYATTNMIGRQIYSSCDWGA------QGCGSG--TNG 237
            ::...:..:||..|........:....|.|........::|...:.||      ..|..|  |||
Human   173 VVWYSSYLVGCGNAYCPNQKVLKYYYVCQYCPAGNWANRLYVPYEQGAPCASCPDNCDDGLCTNG 237

  Fly   238 EFGNLCSTSEWY 249
                 |...:.|
Human   238 -----CKYEDLY 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ag5r2	NP_524689.2	CAP_euk	62..211	CDD:349399	35/153 (23%)
CRISP3	NP_001355052.1	CAP_CRISP	68..205	CDD:349402	36/160 (23%)
		Crisp	222..276	CDD:462519	7/28 (25%)