DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ag5r2 and crispld1

DIOPT Version :9

Sequence 1:	NP_524689.2	Gene:	Ag5r2 / 44079	FlyBaseID:	FBgn0020508	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_002937123.2	Gene:	crispld1 / 100490431	XenbaseID:	XB-GENE-989389	Length:	514	Species:	Xenopus tropicalis

Alignment Length:	277	Identity:	67/277 - (24%)
Similarity:	95/277 - (34%)	Gaps:	86/277 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LALLAILIVSLALAQATD-------YCSSDICNGGSHIACGHSNWWDSSCPGDAELIDINDDYKW 60
            |..:|..:|:|.:..||.       |...|            ..||.:...|...:.:  .|.|
Frog    14 LLFIAQSVVTLVIPNATQLEGLLEKYMDED------------GEWWTAKHRGKRAITE--SDMK- 63

  Fly    61 VFVHSHNDKRNYIAGGYDSNHNAACRMATMEWDDELAYLASLNVRQCNMVHDSCHNTDAFKYSGQ 125
            :.:..||..|..:       :..|..|..|.||.||...|......|...|..   .|.....||
Frog    64 LILDLHNKLRGEV-------YPPASNMEFMIWDVELERSAEAWAETCLWEHGP---ADLLPVIGQ 118

  Fly   126 NLA--WQAYSGDLPDMGYILDNSVQMWFDEVHNSNAGIIAGGYPSGY------------NGPAIG 176
            ||.  |..|.   |...:     ||.|:|||.:         |...|            :||...
Frog   119 NLGAHWGRYR---PPTYH-----VQAWYDEVRD---------YTFPYPQECDPYCPFRCSGPVCT 166

  Fly   177 HFTVMMSERNTRLGCAA-ARYNRDGWNQ-----VLVACNYATT-NMIGRQIY------SSC--DW 226
            |:|.::...::|:|||. ..:|.:.|.|     :.:.|||:.. |..|...|      |:|  .:
Frog   167 HYTQLVWATSSRIGCAINLCHNMNVWGQIWPKAIYLVCNYSPKGNWWGHAPYKHGHPCSACPPSY 231

  Fly   227 GAQGCGSGTNGEFGNLC 243
            |. ||..       |||
Frog   232 GG-GCKD-------NLC 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ag5r2	NP_524689.2	SCP_euk	62..211	CDD:240180	42/168 (25%)
crispld1	XP_002937123.2	CAP_CRISPLD1	62..207	CDD:349407	43/172 (25%)
		LCCL	304..388	CDD:128866
		LCCL	407..506	CDD:367672
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020