DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ran and Ran

DIOPT Version :9

Sequence 1:	NP_001285111.1	Gene:	Ran / 44072	FlyBaseID:	FBgn0020255	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_033417.1	Gene:	Ran / 19384	MGIID:	1333112	Length:	216	Species:	Mus musculus

Alignment Length:	216	Identity:	188/216 - (87%)
Similarity:	198/216 - (91%)	Gaps:	0/216 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAQEGQDIPTFKCVLVGDGGTGKTTFVKRHMTGEFEKKYVATLGVEVHPLIFHTNRGAIRFNVWD 65
            ||.:|:....||.|||||||||||||||||:|||||||||||||||||||:||||||.|:|||||
Mouse     1 MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWD 65

  Fly    66 TAGQEKFGGLRDGYYIQGQCAVIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRK 130
            |||||||||||||||||.|||:|||||||||||||||||||||||||||||||||||||||||||
Mouse    66 TAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRK 130

  Fly   131 VKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGDPNLEFVAMPALLPPEVKMDKDWQA 195
            ||||||||||||||||||||||||||||||||||||||:|||||||||||||.||||.||....|
Mouse   131 VKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAA 195

  Fly   196 QIERDLQEAQATALPDEDEEL 216
            |.|.||:.||.|||||||::|
Mouse   196 QYEHDLEVAQTTALPDEDDDL 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ran	NP_001285111.1	PTZ00132	2..216	CDD:240284	186/213 (87%)
Ran	NP_033417.1	RAN	16..215	CDD:128473	180/198 (91%)
Ran	NP_033417.1	Interaction with RANBP1. /evidence=ECO:0000250\|UniProtKB:P62826	211..216		3/4 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	320	1.000	Domainoid score	I1238
eggNOG	1	0.900	-	-		E1_KOG0096
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68143
Inparanoid	1	1.050	393	1.000	Inparanoid score	I1964
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53961
OrthoDB	1	1.010	-	-		D1083175at2759
OrthoFinder	1	1.000	-	-		FOG0001651
OrthoInspector	1	1.000	-	-		otm42500
orthoMCL	1	0.900	-	-		OOG6_101761
Panther	1	1.100	-	-	LDO	PTHR24071
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1381
SonicParanoid	1	1.000	-	-		X1050
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.870