DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mcr and AI182371

DIOPT Version :9

Sequence 1:	NP_524688.1	Gene:	Mcr / 44071	FlyBaseID:	FBgn0267488	Length:	1760	Species:	Drosophila melanogaster
Sequence 2:	XP_017174840.1	Gene:	AI182371 / 98870	MGIID:	2138853	Length:	366	Species:	Mus musculus

Alignment Length:	244	Identity:	52/244 - (21%)
Similarity:	106/244 - (43%)	Gaps:	49/244 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 FLESLHSREPTYFIVASRMV-RPGLIYQVSV-----------SILQAQYPITVHASIACDGVQIS 173
            |||....:|.|.:|:::.:| |.|....|:|           ::....|| ..:...:...|.:|
Mouse    30 FLEQSWGQEQTRYIISTPIVFRVGAPENVTVQAHGHTEAFDTTVSVKSYP-DENVRYSFSTVNLS 93

  Fly   174 GDSKDVKEGIPETLLMRIPPTSVTGSYKLRVEGFYQNVFGGLAFLNETRLDFSQRSM-------- 230
            .::|     ...|.::.|....::       ||  ||.|.. ::|......|::..:
Mouse    94 PENK-----FQNTAILTIQAKQLS-------EG--QNSFSN-SYLEVVSKHFAKLEIVPIIYDND 143

  Fly   231 TIFVQTDKPLYMQGETVRFRTIPITTELKGFDNPVDVYMLDPNRHILKRWLSRQSNLGSVSL--E 293
            ::||||||.:|...:.|:.|...:..:|:.......:..:||....:.  ....:||..::.  :
Mouse   144 SLFVQTDKSVYTPQQPVKVRVYSVNDDLEPATRETVLTFIDPEGSQVD--TIEGNNLTGIASFPD 206

  Fly   294 YKLSDQPTFGEWTIRVIAQGQQEES-----HFTVEEYYQTRFEVNVTMP 337
            :::...|..|.||::  |:.:::.|     :|.|:||.:| :.::: ||
Mouse   207 FEIPSNPKHGRWTVK--AKYREDASKTGTTYFEVKEYDKT-YRISI-MP 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mcr	NP_524688.1	A2M_N	232..332	CDD:280081	25/106 (24%)
		A2M_N_2	669..799	CDD:285005
		LDLa	886..913	CDD:238060
		A2M	940..1030	CDD:278630
		ISOPREN_C2_like	1177..1490	CDD:298658
		A2M_comp	1226..1492	CDD:284982
		A2M_recep	1607..1695	CDD:284981
AI182371	XP_017174840.1	MG1	42..138	CDD:375333	20/111 (18%)
		A2M_N	145..238	CDD:376626	21/96 (22%)
		ANATO	279..347	CDD:237984
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2373
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810