Protein Alignment Ugt36A1 and Ugt1a6a

DIOPT Version :9

• Sequence 1: NP_001285591.1
• Gene: Ugt36A1 / 44058
• FlyBaseID: FBgn0015663
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_659545.2
• Gene: Ugt1a6a / 94284
• MGIID: 2137698
• Length: 531
• Species: Mus musculus
• Alignment Length: 550
• Identity: 151/550 - (27%)
• Similarity: 244/550 - (44%)
• Gaps: 59/550 - (10%)

  Fly     5 LRSGVLIIVLLGILGIPEPISAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYVKNPQA 69
            |.:|.|.:||...:       .|:.|.|.|..| ||:..:..|:..|:.|||||.|:....|...
Mouse    11 LPAGFLFLVLWASV-------LGDKLLVVPQDG-SHWLSMKEIVEHLSERGHDIMVLVPEVNLLL 67

  Fly    70 GAYPNYEELLISAP-GEDQSSTTINLVPLTEHTPTRSLGVLIREY------VDLHEEGQKTCEHL 127
            |....|...:.|.. ..::..|...........|..||...:|||      ||:.   ...|:.|
Mouse    68 GESKYYRRKIFSVTYSLEELQTRFRTFGNNHFLPGASLMGPLREYRNNMIVVDMF---FSNCQSL 129

  Fly   128 FASGHIERAIERHRNKPYDLLLTEYFNSDCQLALAKLLNLPIIGL---STCALMPYYYDRIDLPD 189
            ...   ...:...|...:|.|.|:. ...|.:.||:.||||.:.|   ..|:|.......   |.
Mouse   130 LKD---SATLSFLRENKFDALFTDP-AMPCGVILAEYLNLPSVYLFRGFPCSLEHMLGQS---PS 187

  Fly   190 TPAFIQSEFVGFAGQLNWHERLLNFVQAKLLKFLY-----KYHSNRADNELVRKYLGVEVDVEEV 249
            ..:::...:..|:..:.:.:||.||:...|..:||     ||....:|  |:::      ||...
Mouse   188 PVSYVPRFYTKFSDHMTFPQRLANFIVNILENYLYYCLYSKYEIIASD--LLKR------DVSLP 244

  Fly   250 ARTQTAFIFGNQHYSLMGSRPQSLQFVEIGGVHITKKAEQELPQNIANFLNQSAE-GVIFISWGS 313
            :..|.:.......:.....||.....:.:||::..||.  :|.|....::|.|.| |::..|.||
Mouse   245 SLHQNSLWLLRYDFVFEYPRPVMPNMIFLGGINCKKKG--KLTQEFEAYVNASGEHGIVVFSLGS 307

  Fly   314 MVRASSIDEDKLSAILEVLKSQPLKIIWKWEADETPDTDASKFLFVKWAPQLALLCHPKVKLFWS 378
            ||  |.|.|.|...|.|.|...|..::|::.... |...|...:.|||.||..||.|||.:.|.:
Mouse   308 MV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTR-PSNLAKNTILVKWLPQNDLLGHPKTRAFIT 369

  Fly   379 HGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDITVPNLKKALAELSKN-SY 442
            |.|..|..|.:..|.|:::.|::|||..||..::.||.|:.|:..::|..:|:.||..:..| ||
Mouse   370 HSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSY 434

  Fly   443 AQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGIELNGFVYHSLDSVALIL--- 504
            .:..:.:|.:..:|...||:.|::.||:|:.:.  .|..|:....:|..:.|||||.:..:|
Mouse   435 KENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHK--GAPHLRPAAHDLTWYQYHSLDVIGFLLAIV 497

  Fly   505 LPLILLILVLC-YLCK-----RNPSKLAHK 528
            |.::.::...| |.|:     :...|.:||
Mouse   498 LTVVFIVFKCCAYGCRKCFGGKGRVKKSHK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_001285591.1	egt	8..475	CDD:223071	134/483 (28%)
		UDPGT	38..501	CDD:278624	133/479 (28%)
Ugt1a6a	NP_659545.2	egt	15..503	CDD:223071	143/520 (28%)
		UDPGT	27..522	CDD:278624	142/520 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840190
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840