Protein Alignment Ugt36A1 and Ugt2b35

DIOPT Version :10

• Sequence 1: NP_524686.3
• Gene: Ugt36A1 / 44058
• FlyBaseID: FBgn0015663
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001004271.1
• Gene: Ugt2b35 / 83808
• RGDID: 620895
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 564
• Identity: 133/564 - (23%)
• Similarity: 260/564 - (46%)
• Gaps: 83/564 - (14%)

  Fly     4 CLRSGVLIIVLLGILGIPEPISAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYVKNPQ 68
            |.:||                :.|.:| |:| ..:||:..:..||.||..:||::||:    .|.
  Rat    17 CFKSG----------------NCGKVL-VWP-MEYSHWMNIKIILEELVQKGHEVTVL----RPS 59

  Fly    69 AGAYPNYEELLISAPGEDQSSTTINLVPLTEHTPTRSLGVLIREYVDL--HEEGQKTCEHLFASG 131
            |..:.:.:|           ::.:..|.......:..|......:|::  :|..:.||...|.
  Rat    60 ASVFLDPKE-----------TSDLKFVTFPTSFSSHDLENFFTRFVNVWTYELPRDTCLSYFL-- 111

  Fly   132 HIERAIERH---------------------RNKPYDLLLTEYFNSDCQLALAKLLNLPI---IGL 172
            :::..|:.:                     :...:|::.::.. ..|...:|:||.:|.   :..
  Rat   112 YLQDTIDEYSDYCLTVCKEAVSNKQFMTKLQESKFDVVFSDAI-GPCGELIAELLQIPFLYSLRF 175

  Fly   173 STCALMPYYYDRIDLPDTPAFIQSEFVGFAGQLNWHERLLNFVQAKLLKFLYKYHSNRADNELVR 237
            |....:..|...:..|  |:::...|.|.|||:.:.||:.|.:......|.::....:..:....
  Rat   176 SPGYTIEKYIGGVLFP--PSYVPMIFSGLAGQMTFIERVHNMICMLYFDFWFQTFREKKWDPFYS 238

  Fly   238 KYLGVEVDVEEVARTQTAFIFGNQHYSLMGSRPQSLQFVEIGGVHITKKAEQELPQNIANFLNQS 302
            |.||....:.|:......::. ..::.|....|.|.....|||:|.  |..:.||::|.:|:..|
  Rat   239 KTLGRPTTLAEIMGKAEMWLI-RSYWDLEFPHPISPNVDYIGGLHC--KPAKPLPKDIEDFVQSS 300

  Fly   303 AE-GVIFISWGSMVRASSIDEDKLSAILEVLKSQPLKIIWKWEADETPDTDASKFLFVKWAPQLA 366
            .| ||:..|.|||||  ::.|:|.:.|...|...|.|::|:::..:.|....:..|: ||.||..
  Rat   301 GEHGVVVFSLGSMVR--NMTEEKANIIAWALAQIPQKVLWRFDGKKPPTLGPNTRLY-KWLPQND 362

  Fly   367 LLCHPKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDITVPNLK 431
            ||.|||.|.|.:|||..|..|::|.|.|::..|::|:|..|...:..:|..::::::.::..::.
  Rat   363 LLGHPKTKAFVTHGGANGIYEAIHHGIPMIGIPLFGEQHDNIAHMVAKGAAVEVNFRTMSKSDML 427

  Fly   432 KALAELSKNS-YAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGIELNGFVYH 495
            .||.|:..|. |.:.::.:|.:.:::...||:.|::.:|.|:.:.  .|:.|:|.|..|..:.||
  Rat   428 NALEEVINNPFYKKNAMWLSTIHHDQPTKPLDRAVFWIEFVMRHK--GAKHLRSLGHNLPWYQYH 490

  Fly   496 SLDSVALIL--LPLILLILVLCYLCKRNPSKLAHKKVGKKPKRS 537
            |||.:..:|  :.:.:::.:.|:|       ..::...||.|::
  Rat   491 SLDVIGFLLTCVAVTVVLALKCFL-------FVYRFFVKKEKKT 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_524686.3	GT1_Gtf-like	28..469	CDD:340817	111/468 (24%)
Ugt2b35	NP_001004271.1	UDPGT	24..527	CDD:278624	130/539 (24%)