DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36A1 and UGT72B3

DIOPT Version :9

Sequence 1:	NP_001285591.1	Gene:	Ugt36A1 / 44058	FlyBaseID:	FBgn0015663	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001322549.1	Gene:	UGT72B3 / 837503	AraportID:	AT1G01420	Length:	484	Species:	Arabidopsis thaliana

Alignment Length:	542	Identity:	112/542 - (20%)
Similarity:	198/542 - (36%)	Gaps:	137/542 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 EPISAGNI--LAVYPHFGFSHFKVVMPILNELAHR-----GHDITVISYVKNPQAGAYPNYEELL 79
            :.::.||.  :|:.|..|..|   ::|:: |||.|     |..:|.|....:|.:.|   ...:|
plant     2 QKMADGNTPHVAIIPSPGIGH---LIPLV-ELAKRLLDNHGFTVTFIIPGDSPPSKA---QRSVL 59

  Fly    80 ISAPGEDQS----STTINLVPLTEHTPTRSLGVLIREYVDLHEEGQKTCEHLFASGHIERAIERH 140
            .|.|....|    ...::.||.|....||....:.|....|.|        ||.|...|:.:..
plant    60 NSLPSSIASVFLPPADLSDVPSTARIETRISLTVTRSNPALRE--------LFGSLSAEKRLPA- 115

  Fly   141 RNKPYDLLLTEYFNSDCQLALAKLLNLPIIGLSTCALMPYYYDRIDLPDTPAFIQSEF------- 198
                  :|:.:.|.:|.....|:....|.|..::.|.:..:.  :.||.....:..||
plant   116 ------VLVVDLFGTDAFDVAAEFHVSPYIFYASNANVLTFL--LHLPKLDETVSCEFRELTEPV 172

  Fly   199 -----VGFAGQLNWHERLLNFV----QAKLLKFLYKYHS----NRADNELVRKYLGVEVD----V 246
                 |...|:        :||    ..|...:.:..|:    ..|:..||..::.:|.:    |
plant   173 IIPGCVPITGK--------DFVDPCQDRKDESYKWLLHNVKRFKEAEGILVNSFVDLEPNTIKIV 229

  Fly   247 EEVARTQ-TAFIFGNQHYSLMGSRPQSLQFVEIGGVHITKKAEQELPQNIANFL-NQSAEGVIFI 309
            :|.|..: ..::.|    .|:.|           |.|   .|:........|:| ||....|:::
plant   230 QEPAPDKPPVYLIG----PLVNS-----------GSH---DADVNDEYKCLNWLDNQPFGSVLYV 276

  Fly   310 SWGSMVRASSIDEDKLSAILEVLKSQPLKIIWKWEADE--------TPDTDASKFLFV------- 359
            |:||   ..::..::...:...|.....:.:|...:..        .|.:....|.|:
plant   277 SFGS---GGTLTFEQFIELALGLAESGKRFLWVIRSPSGIASSSYFNPQSRNDPFSFLPQGFLDR 338

  Fly   360 ---------KWAPQLALLCHPKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRG 415
                     .||||..:|.|..:..|.:|.|...:.||:..|.||:..|:|.:|.:||..:.:.|
plant   339 TKEKGLVVGSWAPQAQILTHTSIGGFLTHCGWNSSLESIVNGVPLIAWPLYAEQKMNALLLVDVG 403

  Fly   416 MGLKLDYQDITVPNLKKALAELSKNSYAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAAR 480
            ..|:               |.|.::....|. ||::|.....:....:|:......:..|  :.|
plant   404 AALR---------------ARLGEDGVVGRE-EVARVVKGLIEGEEGNAVRKKMKELKEG--SVR 450

  Fly   481 LLQSPGIELNGFVYHSLDSVAL 502
            :|:.     :||...||:.|:|
plant   451 VLRD-----DGFSTKSLNEVSL 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_001285591.1	egt	8..475	CDD:223071	103/513 (20%)
Ugt36A1	NP_001285591.1	UDPGT	38..501	CDD:278624	105/521 (20%)
UGT72B3	NP_001322549.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000