Protein Alignment Ugt36A1 and UGT2A3

DIOPT Version :9

• Sequence 1: NP_001285591.1
• Gene: Ugt36A1 / 44058
• FlyBaseID: FBgn0015663
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: XP_011530549.1
• Gene: UGT2A3 / 79799
• HGNCID: 28528
• Length: 533
• Species: Homo sapiens
• Alignment Length: 539
• Identity: 133/539 - (24%)
• Similarity: 256/539 - (47%)
• Gaps: 66/539 - (12%)

  Fly    27 GNILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYVKNPQAGAYPNYEELLISAPGEDQSST- 90
            |.:| |:| ...||:..|..||.||..|||::||:::.| |....|.....|........|..|
Human    24 GKVL-VWP-CDMSHWLNVKVILEELIVRGHEVTVLTHSK-PSLIDYRKPSALKFEVVHMPQDRTE 85

  Fly    91 --------TINLVPLTEHTPTRSLGVLIREYVDLHEEGQKTCEHLFASGHIERAIERHRNKPYDL 147
                    .:|::|  ..:..:|:..|...:|::....:..||...   :.:..:::.:...||:
Human    86 ENEIFVDLALNVLP--GLSTWQSVIKLNDFFVEIRGTLKMMCESFI---YNQTLMKKLQETNYDV 145

  Fly   148 LLTEYFNSDCQLALAKLLNLPII---GLS-------TCALMPYYYDRIDLPDTPAFIQSEFVGFA 202
            :|.:.. ..|...:|:||.:|.:   .:|       :|..:|.....:.:|.|         |..
Human   146 MLIDPV-IPCGDLMAELLAVPFVLTLRISVGGNMERSCGKLPAPLSYVPVPMT---------GLT 200

  Fly   203 GQLNWHERLLNFVQAKLLKFL---YKYHSNRADNELVRKYLGVEVDV-EEVARTQTAFIFGNQHY 263
            .::.:.||:.|.:.:.|..|.   |.||   ...|...|.||....: |.|.:.:...|  ..::
Human   201 DRMTFLERVKNSMLSVLFHFWIQDYDYH---FWEEFYSKALGRPTTLCETVGKAEIWLI--RTYW 260

  Fly   264 SLMGSRPQSLQFVEIGGVHITKKAEQELP------QNIANFLNQSAE-GVIFISWGSMVRASSID 321
            .....:|....|..:||:|.  |..:.||      |.:.||:..|.| |::..|.||:.:  ::.
Human   261 DFEFPQPYQPNFEFVGGLHC--KPAKALPKINFYLQEMENFVQSSGEDGIVVFSLGSLFQ--NVT 321

  Fly   322 EDKLSAILEVLKSQPLKIIWKWEADETPDTDASKFLFVKWAPQLALLCHPKVKLFWSHGGLLGTT 386
            |:|.:.|...|...|.|::|:::. :.|.|..:......|.||..||.|||.|.|.:|||:.|..
Human   322 EEKANIIASALAQIPQKVLWRYKG-KKPSTLGANTRLYDWIPQNDLLGHPKTKAFITHGGMNGIY 385

  Fly   387 ESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDITVPNLKKAL-AELSKNSYAQRSLEVS 450
            |:::.|.|::..||:|||..|...::.:|..::::::.:|..:|.:|| ..::.:||.:.::.:|
Human   386 EAIYHGVPMVGVPIFGDQLDNIAHMKAKGAAVEINFKTMTSEDLLRALRTVITDSSYKENAMRLS 450

  Fly   451 KVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGIELNGFVYHSLDSVALIL--LPLILLILV 513
            ::.:::...||:.|::.:|.|:.:.  .|:.|:|...:|..|.::|:|.:..:|  :...:.:..
Human   451 RIHHDQPVKPLDRAVFWIEFVMRHK--GAKHLRSAAHDLTWFQHYSIDVIGFLLACVATAIFLFT 513

  Fly   514 LCYL--CKR-NPSKLAHKK 529
            .|:|  |:: |.::...|:
Human   514 KCFLFSCQKFNKTRKIEKR 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_001285591.1	egt	8..475	CDD:223071	120/478 (25%)
		UDPGT	38..501	CDD:278624	123/493 (25%)
UGT2A3	XP_011530549.1	UDPGT	24..528	CDD:278624	132/533 (25%)
		egt	<267..498	CDD:223071	69/237 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150099
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840