Protein Alignment Ugt36A1 and ugt5c2

DIOPT Version :10

• Sequence 1: NP_524686.3
• Gene: Ugt36A1 / 44058
• FlyBaseID: FBgn0015663
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001038851.1
• Gene: ugt5c2 / 751669
• ZFINID: ZDB-GENE-060825-206
• Length: 552
• Species: Danio rerio
• Alignment Length: 547
• Identity: 140/547 - (25%)
• Similarity: 247/547 - (45%)
• Gaps: 82/547 - (14%)

  Fly    11 IIVLLGILGIPEPISAGNILAVYPHFGFSHFKVVMPILNELAH-RGHDITVIS-----YVKNPQA 69
            :|.:.|.|     ...|.|| |.|..| ||: |.|.||.:..| :||.:.||.     ::|  :.
Zfish    38 VITIFGSL-----CDGGKIL-VAPLEG-SHW-VNMDILIKALHGQGHTVDVIRNANSWFIK--EN 92

  Fly    70 GAYPNYEELLI-SAPGEDQSSTTINLVPLTEHTPTRSLGV-LIREYVDLHEEGQKT----CEHLF 128
            ..|  |:.:.| :..|.|:......:..:.::...:...: ::|.|:::.:..:||    |:.:.
Zfish    93 STY--YDTITIPNTKGWDEEFAADFVYKMIKYEKEKGSWLSIVRLYLNVFDAVKKTHEMVCQLIT 155

  Fly   129 ASGHIERAIERHRNKPYDLLLTE-YFNSDCQLALAKLLNLPIIGLSTCALMPYYYD--------- 183
            .....|..::....|.|||:||: .:.:.  :.||..|.||::           |:
Zfish   156 NILDSEEILKMLNEKQYDLMLTDPVWGTG--IILAHKLKLPMV-----------YNVRWTTTGEG 207

  Fly   184 RIDLPDTP-AFIQSEFVGFAGQLNWHERLLNFVQAKLLKFLYKYHSNRADNELVRKYLGVEVDVE 247
            ..|:..:| ::|.....|...::::.:||.|:....||.....:.:.:....:..||....|:..
Zfish   208 HFDIAPSPMSYIPITGSGNTDRMSFFQRLKNYFFYLLLDLQLSHFNVKQYQAICDKYFTSRVNFH 272

  Fly   248 E--------VARTQTAFIFGNQHYSLMGSRPQSLQFVEIGGVHITKKAEQELPQNIANFLNQSAE 304
            |        :.|....|.|         .||.....:.|||...  ...:.||.::.:|:..|.:
Zfish   273 ELLQGADLWLMRVDFVFEF---------PRPTMPNIIYIGGFQC--PPAKPLPHDLEDFMQSSGD 326

  Fly   305 -GVIFISWGSMVRASSIDEDKLSAILEVLKSQPLKIIWKWEADETPDTDASKFLFVKWAPQLALL 368
             |||.:|.||::  .::.|:..:.|.......|.|:||:: ..:.|.|.::..|.|.|.||..||
Zfish   327 HGVIVMSLGSLI--GNLPENVTAEIAAAFARLPQKVIWRY-TGKKPSTLSNNTLMVDWMPQKDLL 388

  Fly   369 CHPKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDITVPNLKKA 433
            .|||.|:|.||||..|..|:::.|.|::..|.:.||:.|...:|.||....|...|:....|..|
Zfish   389 GHPKTKVFISHGGTNGVLEALYHGVPVIGIPFFFDQYDNLIRLQARGGAKLLSIADLGENTLHAA 453

  Fly   434 LAE-LSKNSYAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGIELNGFVYHSL 497
            :.| :::.||.....::|.:..::...||:|||:.:|.|:.:.  .|..|::...::..:.|||:
Zfish   454 IQEVINEPSYRLNMHKLSHLHKDKPVKPLDSAIFWIEFVMRHK--GAAHLRTESYKMPWYSYHSV 516

  Fly   498 DSVALILLPLILLILVLC------YLC 518
            |.|  :.|..::|||..|      |||
Zfish   517 DVV--VTLFAVVLILTYCIFVTVRYLC 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_524686.3	GT1_Gtf-like	28..469	CDD:340817	119/473 (25%)
ugt5c2	NP_001038851.1	UDPGT	49..551	CDD:278624	137/531 (26%)