Protein Alignment Ugt36A1 and UGT8

DIOPT Version :9

• Sequence 1: NP_001285591.1
• Gene: Ugt36A1 / 44058
• FlyBaseID: FBgn0015663
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001121646.2
• Gene: UGT8 / 7368
• HGNCID: 12555
• Length: 541
• Species: Homo sapiens
• Alignment Length: 532
• Identity: 136/532 - (25%)
• Similarity: 255/532 - (47%)
• Gaps: 50/532 - (9%)

  Fly    12 IVLLGILGIPEPISAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYVKNPQAGAYPNYE 76
            |:|...:||.:   |..|:.|.|....||..:...:.:.|..|||. ||  ::.:......|:..
Human     9 ILLWSAVGIAK---AAKIIIVPPIMFESHMYIFKTLASALHERGHH-TV--FLLSEGRDIAPSNH 67

  Fly    77 ELLISAPGEDQSSTTINLVPLTEHTPTRSL--GVLIR-EYVDLHEEGQKTCEHLFASGHIERAIE 138
            ..|...||...|:|:...:    .:..|::  |.|.. |..|:.:...|.|: |....|  ..|:
Human    68 YSLQRYPGIFNSTTSDAFL----QSKMRNIFSGRLTAIELFDILDHYTKNCD-LMVGNH--ALIQ 125

  Fly   139 RHRNKPYDLLLTEYFNSDCQLALAKLLNLPIIGLSTCALMPYYYDRIDLPDTPAFIQSEFVGFAG 203
            ..:.:.:||||.:. |..|...:|.||.:.....||..   :|...:..|...|::.........
Human   126 GLKKEKFDLLLVDP-NDMCGFVIAHLLGVKYAVFSTGL---WYPAEVGAPAPLAYVPEFNSLLTD 186

  Fly   204 QLNWHERLLN---FVQAKL-LKFLY--KYHSNRADNELVRKY-LGVEVDVEEVARTQTAFIFGNQ 261
            ::|..:|:.|   ::.::| :.||.  ||      ..:::|| |..|..:.::....:.::....
Human   187 RMNLLQRMKNTGVYLISRLGVSFLVLPKY------ERIMQKYNLLPEKSMYDLVHGSSLWMLCTD 245

  Fly   262 HYSLMGSRPQSLQFVEIGGVHITKKAEQELPQNIANFLNQSAE-GVIFISWGSMVRASSIDEDKL 325
             .:|...||.....|.:||: :||.| ..||:::..::|.:.| |.:.:|:|:.|:  .:.||..
Human   246 -VALEFPRPTLPNVVYVGGI-LTKPA-SPLPEDLQRWVNGANEHGFVLVSFGAGVK--YLSEDIA 305

  Fly   326 SAILEVLKSQPLKIIWKWEADETPDTDASKFLFVKWAPQLALLCHPKVKLFWSHGGLLGTTESVH 390
            :.:...|...|.|:||::...: |....:....::|.||..||.|.|:|.|.|||||....|:::
Human   306 NKLAGALGRLPQKVIWRFSGPK-PKNLGNNTKLIEWLPQNDLLGHSKIKAFLSHGGLNSIFETIY 369

  Fly   391 CGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDITVPNLKKALAELSKN-SYAQRSLEVSKVFN 454
            .|.|::..|::||.:.....||.:|||:.|:::.:|...|.:||.::..| ||.||:.::|::..
Human   370 HGVPVVGIPLFGDHYDTMTRVQAKGMGILLEWKTVTEKELYEALVKVINNPSYRQRAQKLSEIHK 434

  Fly   455 ERQQTPLESAIWSVEHVI-SNGLIAARLLQSPGIELNGFVYHSLDSVALILLPLILLILVLCYLC 518
            ::...|:...|:.::::| .||   |..|::...:::...|..||...::||...||..:|.::
Human   435 DQPGHPVNRTIYWIDYIIRHNG---AHHLRAAVHQISFCQYFLLDIAFVLLLGAALLYFLLSWV- 495

  Fly   519 KRNPSKLAHKKV 530
                :|..::|:
Human   496 ----TKFIYRKI 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_001285591.1	egt	8..475	CDD:223071	122/475 (26%)
		UDPGT	38..501	CDD:278624	121/475 (25%)
UGT8	NP_001121646.2	Glycosyltransferase_GTB-type	21..502	CDD:415824	130/514 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150171
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840