Protein Alignment Ugt36A1 and UGT2B17

DIOPT Version :9

• Sequence 1: NP_001285591.1
• Gene: Ugt36A1 / 44058
• FlyBaseID: FBgn0015663
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001068.1
• Gene: UGT2B17 / 7367
• HGNCID: 12547
• Length: 530
• Species: Homo sapiens
• Alignment Length: 569
• Identity: 146/569 - (25%)
• Similarity: 250/569 - (43%)
• Gaps: 118/569 - (20%)

  Fly    25 SAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYVKNPQAGAYPNYEELLISAPGEDQSS 89
            |.|.:| |:| ..:||:..:..||.||..|||::.|::           :...:|::|    ..|
Human    22 SCGKVL-VWP-TEYSHWINMKTILEELVQRGHEVIVLT-----------SSASILVNA----SKS 69

  Fly    90 TTINLVPLTEHTPT-------------------------------RSLGVLIREYVDLHEEGQKT 123
            :.|.|    |..||                               ..|..|..||.|.:   .|.
Human    70 SAIKL----EVYPTSLTKNDLEDFFMKMFDRWTYSISKNTFWSYFSQLQELCWEYSDYN---IKL 127

  Fly   124 CEHLFASGHIERAIERHRNKPYDLLLTEYFNSDCQLALAKLLNLPIIGLSTCALMPYYYDRIDLP 188
            ||....:..:.|.::..:   :|:||.:..| .|...||:|||:|.:          |..|..:.
Human   128 CEDAVLNKKLMRKLQESK---FDVLLADAVN-PCGELLAELLNIPFL----------YSLRFSVG 178

  Fly   189 DT-----------PAFIQSEFVGFAGQLNWHERLLNFVQAKLLKFLYKYHSNRADNELVRKYLGV 242
            .|           |:::.......:.|:.:.||:.|.:......|.::.:..:..::...:.||.
Human   179 YTVEKNGGGFLFPPSYVPVVMSELSDQMIFMERIKNMIYMLYFDFWFQAYDLKKWDQFYSEVLGR 243

  Fly   243 EVDVEE--------VARTQTAFIFGNQHYSLMGSRP--QSLQFVEIGGVHITKKAEQELPQNIAN 297
            ...:.|        :.||...|.|         .||  .::.||  ||:|.  |..:.||:.:..
Human   244 PTTLFETMGKAEMWLIRTYWDFEF---------PRPFLPNVDFV--GGLHC--KPAKPLPKEMEE 295

  Fly   298 FLNQSAE-GVIFISWGSMVRASSIDEDKLSAILEVLKSQPLKIIWKWEADETPDTDASKFLFVKW 361
            |:..|.| |::..|.|||:  |::.|:..:.|...|...|.|::|:::. :.|:|..|.....||
Human   296 FVQSSGENGIVVFSLGSMI--SNMSEESANMIASALAQIPQKVLWRFDG-KKPNTLGSNTRLYKW 357

  Fly   362 APQLALLCHPKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDIT 426
            .||..||.|||.|.|.:|||..|..|:::.|.|::..|::.||..|...::.:|..|.:|.:.::
Human   358 LPQNDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRTMS 422

  Fly   427 VPNLKKALAELSKNS-YAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGIELN 490
            ..:|..||..:..:. |.:..:::|::.:::...||:.|::.:|.|:.:.  .|:.|:.....|.
Human   423 SRDLLNALKSVINDPIYKENIMKLSRIHHDQPVKPLDRAVFWIEFVMRHK--GAKHLRVAAHNLT 485

  Fly   491 GFVYHSLDSVALIL---LPLILLILVLCYLCKRNPSKLAHKKVGKKPKR 536
            ...|||||.:|.:|   ..:|.:|...|..|.|   |||  |.|||.||
Human   486 WIQYHSLDVIAFLLACVATMIFMITKCCLFCFR---KLA--KTGKKKKR 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_001285591.1	egt	8..475	CDD:223071	122/503 (24%)
		UDPGT	38..501	CDD:278624	125/516 (24%)
UGT2B17	NP_001068.1	UDPGT	24..518	CDD:278624	135/549 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150106
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840