Protein Alignment Ugt36A1 and UGT2B15

DIOPT Version :9

• Sequence 1: NP_001285591.1
• Gene: Ugt36A1 / 44058
• FlyBaseID: FBgn0015663
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001067.2
• Gene: UGT2B15 / 7366
• HGNCID: 12546
• Length: 530
• Species: Homo sapiens
• Alignment Length: 560
• Identity: 138/560 - (24%)
• Similarity: 254/560 - (45%)
• Gaps: 100/560 - (17%)

  Fly    25 SAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYVKNPQAGAYPNYEELLISAPGEDQSS 89
            |.|.:| |:| ..:||:..:..||.||..|||::||::           :....|::|  ...|:
Human    22 SCGKVL-VWP-TEYSHWINMKTILEELVQRGHEVTVLT-----------SSASTLVNA--SKSSA 71

  Fly    90 TTINLVP--LTEHTPTRSLGVLIREYV--------------------DLHEEGQKTCEHLFASGH 132
            ..:.:.|  ||::....||..::..::                    :.::...|.|:....:
Human    72 IKLEVYPTSLTKNYLEDSLLKILDRWIYGVSKNTFWSYFSQLQELCWEYYDYSNKLCKDAVLN-- 134

  Fly   133 IERAIERHRNKPYDLLLTEYFNSDCQLALAKLLNLPIIGLSTCALMPYYYDRIDLPDT------- 190
             ::.:.:.:...:|::|.:..| .|...||:|.|:|.:          |..|..:..|
Human   135 -KKLMMKLQESKFDVILADALN-PCGELLAELFNIPFL----------YSLRFSVGYTFEKNGGG 187

  Fly   191 ----PAFIQSEFVGFAGQLNWHERLLNFVQAKLLKFLYKYHSNRADNELVRKYLGVEVDVEE--- 248
                |:::.......:.|:.:.||:.|.:......|.::.:..:..::...:.||....:.|
Human   188 FLFPPSYVPVVMSELSDQMIFMERIKNMIHMLYFDFWFQIYDLKKWDQFYSEVLGRPTTLFETMG 252

  Fly   249 -----VARTQTAFIFGNQHYSLMGSRP--QSLQFVEIGGVHITKKAEQELPQNIANFLNQSAE-G 305
                 :.||...|.|         .||  .::.||  ||:|.  |..:.||:.:..|:..|.| |
Human   253 KAEMWLIRTYWDFEF---------PRPFLPNVDFV--GGLHC--KPAKPLPKEMEEFVQSSGENG 304

  Fly   306 VIFISWGSMVRASSIDEDKLSAILEVLKSQPLKIIWKWEADETPDTDASKFLFVKWAPQLALLCH 370
            ::..|.|||:  |::.|:..:.|...|...|.|::|:::. :.|:|..|.....||.||..||.|
Human   305 IVVFSLGSMI--SNMSEESANMIASALAQIPQKVLWRFDG-KKPNTLGSNTRLYKWLPQNDLLGH 366

  Fly   371 PKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDITVPNLKKALA 435
            ||.|.|.:|||..|..|:::.|.|::..|::.||..|...::.:|..|.:|.:.::..:|..||.
Human   367 PKTKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRTMSSRDLLNALK 431

  Fly   436 ELSKNS-YAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGIELNGFVYHSLDS 499
            .:..:. |.:..:::|::.:::...||:.|::.:|.|:.:.  .|:.|:.....|....|||||.
Human   432 SVINDPVYKENVMKLSRIHHDQPMKPLDRAVFWIEFVMRHK--GAKHLRVAAHNLTWIQYHSLDV 494

  Fly   500 VALIL---LPLILLILVLCYLCKRNPSKLAHKKVGKKPKR 536
            :|.:|   ..:|.:|...|..|.|   |||.|  |||.||
Human   495 IAFLLACVATVIFIITKFCLFCFR---KLAKK--GKKKKR 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_001285591.1	egt	8..475	CDD:223071	114/494 (23%)
		UDPGT	38..501	CDD:278624	117/507 (23%)
UGT2B15	NP_001067.2	egt	8..508	CDD:223071	125/532 (23%)
		UDPGT	24..518	CDD:278624	127/540 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150107
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840