Protein Alignment Ugt36A1 and UGT2B4

DIOPT Version :9

• Sequence 1: NP_001285591.1
• Gene: Ugt36A1 / 44058
• FlyBaseID: FBgn0015663
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_066962.2
• Gene: UGT2B4 / 7363
• HGNCID: 12553
• Length: 528
• Species: Homo sapiens
• Alignment Length: 557
• Identity: 132/557 - (23%)
• Similarity: 253/557 - (45%)
• Gaps: 96/557 - (17%)

  Fly    25 SAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYVKNPQAGAYPNYEELLISAPGEDQSS 89
            |.|.:| |:| ..|||:..:..||:||..|||::||::  .:......||             |.
Human    22 SCGKVL-VWP-TEFSHWMNIKTILDELVQRGHEVTVLA--SSASISFDPN-------------SP 69

  Fly    90 TTINL----VPLTEHTPTRSLGVLIREYVDLHEEG-------------------QKTCEHLFASG 131
            :|:..    |.||:......:..|::.:.:|.::.                   :|.|:.:.::.
Human    70 STLKFEVYPVSLTKTEFEDIIKQLVKRWAELPKDTFWSYFSQVQEIMWTFNDILRKFCKDIVSNK 134

  Fly   132 HIERAIERHRNKPYDLLLTEYFNSDCQLALAKLLNLPII----------------GLSTCALMPY 180
            .:.:.::..|   :|::|.:......:| ||:||.:|.:                ||    |.|
Human   135 KLMKKLQESR---FDVVLADAVFPFGEL-LAELLKIPFVYSLRFSPGYAIEKHSGGL----LFP- 190

  Fly   181 YYDRIDLPDTPAFIQSEFVGFAGQLNWHERLLNFVQAKLLKFLYKYHSNRADNELVRKYLGVEVD 245
                      |:::.......:.|:.:.||:.|.:.....:|.::....:..::...:.||....
Human   191 ----------PSYVPVVMSELSDQMTFIERVKNMIYVLYFEFWFQIFDMKKWDQFYSEVLGRPTT 245

  Fly   246 VEEVARTQTAFIFGNQHYSLMGSRP--QSLQFVEIGGVHITKKAEQELPQNIANFLNQSAE-GVI 307
            :.|.......::..| ::......|  .:::||  ||:|.  |..:.||:.:..|:..|.| ||:
Human   246 LSETMAKADIWLIRN-YWDFQFPHPLLPNVEFV--GGLHC--KPAKPLPKEMEEFVQSSGENGVV 305

  Fly   308 FISWGSMVRASSIDEDKLSAILEVLKSQPLKIIWKWEADETPDTDASKFLFVKWAPQLALLCHPK 372
            ..|.||||  |:..|::.:.|...|...|.|::|:::.:: |||........||.||..||.|||
Human   306 VFSLGSMV--SNTSEERANVIASALAKIPQKVLWRFDGNK-PDTLGLNTRLYKWIPQNDLLGHPK 367

  Fly   373 VKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDITVPNLKKALAEL 437
            .:.|.:|||..|..|:::.|.|::..|::.||..|...::.:|..:.||:..::..:|..||..:
Human   368 TRAFITHGGANGIYEAIYHGIPMVGVPLFADQPDNIAHMKAKGAAVSLDFHTMSSTDLLNALKTV 432

  Fly   438 SKNS-YAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGIELNGFVYHSLDSVA 501
            ..:. |.:.::::|::.:::...||:.|::.:|.|:.:.  .|:.|:....:|..|.|||||...
Human   433 INDPLYKENAMKLSRIHHDQPVKPLDRAVFWIEFVMRHK--GAKHLRVAAHDLTWFQYHSLDVTG 495

  Fly   502 LIL--LPLILLILVLCYLCKRNPSKLAHKKVGKKPKR 536
            .:|  :..::.|:..|..|     .....:.|||.||
Human   496 FLLACVATVIFIITKCLFC-----VWKFVRTGKKGKR 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_001285591.1	egt	8..475	CDD:223071	114/492 (23%)
		UDPGT	38..501	CDD:278624	118/505 (23%)
UGT2B4	NP_066962.2	egt	8..512	CDD:223071	125/535 (23%)
		UDPGT	24..524	CDD:278624	127/550 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150135
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840