Protein Alignment Ugt36A1 and ugt5b6

DIOPT Version :10

• Sequence 1: NP_524686.3
• Gene: Ugt36A1 / 44058
• FlyBaseID: FBgn0015663
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001035435.1
• Gene: ugt5b6 / 678597
• ZFINID: ZDB-GENE-060421-3572
• Length: 531
• Species: Danio rerio
• Alignment Length: 566
• Identity: 129/566 - (22%)
• Similarity: 248/566 - (43%)
• Gaps: 94/566 - (16%)

  Fly     9 VLIIVLLGILGIPEPISAGNILAVYPHFGFSHFKVVMPILNELAH-RGHDITVIS-----YVKNP 67
            |::.|.|.||.:..|:.....:.|:| ...||: |.|.||.|..| :||:|||:.     |:|.
Zfish     8 VILPVTLTILLVTVPVVQSGKVLVFP-VDVSHW-VNMKILVEALHAKGHNITVMRMADSWYIKE- 69

  Fly    68 QAGAYPNYEELLISAP---GEDQSSTTINLVPLTEHTPTRSLGVLIRE-----YVDLHEEGQKTC 124
               ..|:|..:.:.:.   |||          ..|...:|.:.:| ||     .:.|..|..:|.
Zfish    70 ---FSPHYTSINLKSAGGFGED----------FLETFASRLMAIL-REGSIWGRLKLEAEVWQTT 120

  Fly   125 EHLFASGHI--------ERAIERHRNKPYDLLLTE--YFNSDCQLALAKLLNLPIIGLSTCALMP 179
            ..:..:..:        ::.::..::..||::||:  .|..   :.|...|.||::..:...:..
Zfish   121 WKMIETESVMIVNMIEDQKLMQLLKDAKYDVILTDPTIFGG---VILGHYLKLPMVYNARWTIYS 182

  Fly   180 YYYDRIDLPDTPAFIQSEFVGFAGQLNWHERLLNFVQAKLLKFLYKYHSNRADNELVRKYLGVEV 244
            ..:..| .|...:::....:..:.::::.||:.|.|...:::..........::.|..:::|.
Zfish   183 EAHFAI-APSPLSYVPFPSLELSDRMSFLERVCNVVMYTIIEIGAALVIAPINDALAERFIGP-- 244

  Fly   245 DVEEVARTQTAFIFGNQHYSLMGS---------------RPQSLQFVEIGGVHITKKAEQELPQN 294
                          |..:.||:..               ||.....|.:.|...  |..:.|||:
Zfish   245 --------------GTSYLSLVQGADLWLHRVDFVFEYPRPTMPNIVYMAGFQC--KPSKPLPQD 293

  Fly   295 IANFLNQSAE-GVIFISWGSMVRASSIDEDKLSAILEVLKSQPLKIIWKWEADETPDTDASKFLF 358
            :.:|:..|.: |||.:|.|:::  ..:.||...||.|.....|.||||:::. :.|....:..|.
Zfish   294 LEDFVQSSGDHGVIIMSLGTLI--GQLPEDVAEAIAEAFAELPQKIIWRYKG-KRPSALGNNTLV 355

  Fly   359 VKWAPQLALLCHPKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQ 423
            :.|.||..||.|.|.:.|.:|||..|..|:::.|.|::...:..||..|...::.||....:|:.
Zfish   356 MDWMPQNDLLGHSKTRAFVAHGGTNGVQEAIYHGVPIIGFGLIFDQPDNLSKMRVRGAAKNVDFA 420

  Fly   424 DITVPNLKKALAELSKN-SYAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGI 487
            .:...:..|.:.|:..| :|.:....:|::..:....||::||:.:|.|:.:.  .|..|::...
Zfish   421 TMDKESFLKTVKEVLYNPTYRENMQRLSRLHKDVPVKPLDNAIFWIEFVMRHK--GAAHLRTESN 483

  Fly   488 ELNGFVYHSLDSVALILLPLILLILVL--------CYLC-KRNPSK 524
            ::..:.|||:|.:.:::..:.|:||.:        |.:| |:..||
Zfish   484 KMPWYSYHSVDVILVLISAVSLIILTIFAVIRYFCCRICMKKTKSK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_524686.3	GT1_Gtf-like	28..469	CDD:340817	107/481 (22%)
ugt5b6	NP_001035435.1	Glycosyltransferase_GTB-type	27..529	CDD:471961	121/545 (22%)