Protein Alignment Ugt36A1 and Ugt2a2

DIOPT Version :9

• Sequence 1: NP_001285591.1
• Gene: Ugt36A1 / 44058
• FlyBaseID: FBgn0015663
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001019319.1
• Gene: Ugt2a2 / 552899
• MGIID: 3576095
• Length: 528
• Species: Mus musculus
• Alignment Length: 562
• Identity: 143/562 - (25%)
• Similarity: 263/562 - (46%)
• Gaps: 80/562 - (14%)

  Fly    13 VLLGILGIPEPISAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYVK----NPQAGAYP 73
            :|:..|.:.|.:.:||:: |:|..| ||:..:..:|.||..|.|.:||::..:    |.:..|:.
Mouse     8 LLIFHLTLAEIVLSGNVV-VWPTDG-SHWLNIKILLEELVQRNHSVTVLAPSETLFINSRLDAFI 70

  Fly    74 NYEELLISAPGEDQSSTTINLVPL-TEHTPT--------RSLGVLIREYVDLHEEGQKTCEHLFA 129
            |:||:.:|...........:::.| .:|.||        :.||.|:..:   :...::.|:.:..
Mouse    71 NFEEIPVSYTKSKIDEIIEHMIALWLDHRPTPLTMWTFYKELGNLLATF---YTTNKQMCDGVLN 132

  Fly   130 SGHIERAIERHRNKPYDLLLTEYFNSDCQLALAKLLNLPIIGLSTCALMPYYYDRIDLPDTPAFI 194
            :..:   :||.:...:|:||.:......:|...||      |:      |:.|   .|..:|||.
Mouse   133 NPTV---MERLQKGGFDVLLADPVTMCGELVALKL------GI------PFVY---TLRFSPAFT 179

  Fly   195 QSEFVG---------------FAGQLNWHERLLNFVQAKLLKFLYKYHSNRADNELVRKYLGVEV 244
            .....|               ...|:::.||:.|.:...|..:::|.:.... |....|.||...
Mouse   180 VERHCGKIPAPISYVPAALSELTDQMSFGERVKNIISYSLQDYIFKTYWGEW-NSYYSKVLGRPT 243

  Fly   245 DVEE--------VARTQTAFIFGNQHYSLMGSRPQSLQFVEIGGVHITKKAEQELPQNIANFLNQ 301
            .:.|        :.||...|.|         .||....|..:||:|.  |..:.||:.:..|:..
Mouse   244 TLCETMGKAEIWLMRTYWDFEF---------PRPYLPNFEFVGGLHC--KPAKPLPKEMEEFVQT 297

  Fly   302 SAE-GVIFISWGSMVRASSIDEDKLSAILEVLKSQPLKIIWKWEADETPDTDASKFLFVKWAPQL 365
            |.| |::..|.||||:  ::.::|.:.|...|...|.|::|:::. :.|||..|......|.||.
Mouse   298 SGEHGIVVFSLGSMVK--NLTDEKANLIASALAQIPQKVLWRYKG-KIPDTLGSNTRLFDWIPQN 359

  Fly   366 ALLCHPKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDITVPNL 430
            .||.|||.:.|.:|||..|..|:::.|.|::..|::.||..|...::.:|..::::...:|..:|
Mouse   360 DLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDL 424

  Fly   431 KKAL-AELSKNSYAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGIELNGFVY 494
            ..|| ..:::.||.:.::.:|::.:::...||:.|::.:|.|:.:.  .|:.|:....:|:.|.|
Mouse   425 LNALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHK--GAKHLRVAAHDLSWFQY 487

  Fly   495 HSLDSVALILLPLILLILVLCYLCKRNPSKLAHKKVGKKPKR 536
            ||||.:..:|..:...||::...|.....|:.  |.|||.||
Mouse   488 HSLDVIGFLLACVASAILLVAKCCLFIFQKVG--KTGKKKKR 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_001285591.1	egt	8..475	CDD:223071	123/499 (25%)
		UDPGT	38..501	CDD:278624	124/500 (25%)
Ugt2a2	NP_001019319.1	UDPGT	22..516	CDD:278624	133/533 (25%)
		egt	<267..487	CDD:223071	65/226 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840113
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840