Protein Alignment Ugt36A1 and UGT2B28

DIOPT Version :9

• Sequence 1: NP_001285591.1
• Gene: Ugt36A1 / 44058
• FlyBaseID: FBgn0015663
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_444267.1
• Gene: UGT2B28 / 54490
• HGNCID: 13479
• Length: 529
• Species: Homo sapiens
• Alignment Length: 565
• Identity: 136/565 - (24%)
• Similarity: 257/565 - (45%)
• Gaps: 77/565 - (13%)

  Fly     7 SGVLIIVLLGILGIPEPISAGNILAVYPHFG-FSHFKVVMPILNELAHRGHDITVI----SYVKN 66
            :.||:::.||..     .|:|:...|....| :||:..:..||.||..|||::||:    |.:.:
Human     6 TSVLLLIHLGCY-----FSSGSCGKVLVWTGEYSHWMNMKTILKELVQRGHEVTVLASSASILFD 65

  Fly    67 PQAGAYPNYEELLISAPGEDQSSTTINLVPLTEHTPTRSLGVL---IREYVDL------------ 116
            |                 .|..:..:.:.| |..|.|....::   ::.:.|:
Human    66 P-----------------NDAFTLKLEVYP-TSLTKTEFENIIMQQVKRWSDIQKDSFWLYFSQE 112

  Fly   117 -------HEEGQKTCEHLFASGHIERAIERHRNKPYDLLLTEYFNSDCQLALAKLLNLPIIGLST 174
                   |:..:..|:.:.::..:.:.::..|   :|::..:.| ..|...||.|||:|.: .|.
Human   113 QEILWEFHDIFRNFCKDVVSNKKVMKKLQESR---FDIIFADAF-FPCGELLAALLNIPFV-YSL 172

  Fly   175 CALMPYYYDR----IDLPDTPAFIQSEFVGFAGQLNWHERLLNFVQAKLLKFLYKYHSNRADNEL 235
            |....|..:|    :..|  |::|.......:.|:.:.||:.|.:......|.::....:..::.
Human   173 CFTPGYTIERHSGGLIFP--PSYIPVVMSKLSDQMTFMERVKNMIYVLYFDFWFQMCDMKKWDQF 235

  Fly   236 VRKYLGVEVDVEEVARTQTAFIFGNQHYSLMGSRP--QSLQFVEIGGVHITKKAEQELPQNIANF 298
            ..:.||....:.|.......::..|. :|.....|  .::.||  ||:|.  |..:.||:.:..|
Human   236 YSEVLGRPTTLFETMGKADIWLMRNS-WSFQFPHPFLPNIDFV--GGLHC--KPAKPLPKEMEEF 295

  Fly   299 LNQSAE-GVIFISWGSMVRASSIDEDKLSAILEVLKSQPLKIIWKWEADETPDTDASKFLFVKWA 362
            :..|.| ||:..|.||::  |::..::.:.|...|...|.|::|:::.:: ||.........||.
Human   296 VQSSGENGVVVFSLGSVI--SNMTAERANVIATALAKIPQKVLWRFDGNK-PDALGLNTRLYKWI 357

  Fly   363 PQLALLCHPKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDITV 427
            ||..||..||.:.|.:|||..|..|:::.|.|::..|::.||..|...::.:|..::||:..::.
Human   358 PQNDLLGLPKTRAFITHGGANGIYEAIYHGIPMVGIPLFWDQPDNIAHMKAKGAAVRLDFHTMSS 422

  Fly   428 PNLKKAL-AELSKNSYAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGIELNG 491
            .:|..|| ..::..||.:..:::|.:.:::...||..|::.:|.|:.:.  .|:.|:....:|..
Human   423 TDLLNALKTVINDPSYKENVMKLSIIQHDQPVKPLHRAVFWIEFVMCHK--GAKHLRVAARDLTW 485

  Fly   492 FVYHSLDSVALILLPLILLILVLCYLCKRNPSKLAHKKVGKKPKR 536
            |.|||||.:..:|..:..:|.|:...|.....|.|.|  |||.||
Human   486 FQYHSLDVIGFLLACVATVIFVVTKFCLFCFWKFARK--GKKGKR 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_001285591.1	egt	8..475	CDD:223071	115/501 (23%)
		UDPGT	38..501	CDD:278624	116/496 (23%)
UGT2B28	NP_444267.1	UDPGT	24..525	CDD:278624	126/537 (23%)
		egt	<269..506	CDD:223071	69/245 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150147
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840