Protein Alignment Ugt36A1 and Ugt2b35

DIOPT Version :9

• Sequence 1: NP_001285591.1
• Gene: Ugt36A1 / 44058
• FlyBaseID: FBgn0015663
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_766469.1
• Gene: Ugt2b35 / 243085
• MGIID: 3576100
• Length: 529
• Species: Mus musculus
• Alignment Length: 552
• Identity: 141/552 - (25%)
• Similarity: 256/552 - (46%)
• Gaps: 75/552 - (13%)

  Fly     1 MTTCLRSGVLIIVLLGILGIPEPISAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYVK 65
            |:.|.||                .|.|.:| |:| ..|||:..:..||:||..|||::||:
Mouse    14 MSCCFRS----------------TSCGKVL-VWP-LEFSHWMNLKIILDELVQRGHEVTVL---- 56

  Fly    66 NPQAGAY--PNYE-----ELLISAPGEDQSSTTINLVPLTEHT------PTRSLGVLIREYVDLH 117
            .|.|..:  |.|.     |...:|..:|...|.:..: :.|.|      ...|..:|...:..|.
Mouse    57 RPSASIFVDPKYSPGLKFETFPTAFSKDYLETFLTKL-VDEWTFEVPRDTCLSYSLLQTLFGKLS 120

  Fly   118 EEGQKTCEHLFASGHIERAIERHRNKPYDLLLTEYFNSDCQLALAKLLNLPIIGLSTCALMPYYY 182
            :.....|:...::   ::.:.:.:...:|:|:.:...| |...:|:||.:|.  |.:....|.|
Mouse   121 DYSLSLCKEAVSN---KQLMTKFQESKFDVLILDAMAS-CGELIAQLLQIPF--LYSLRFSPGY- 178

  Fly   183 DRID-------LPDTPAFIQSEFVGFAGQLNWHERLLNFVQAKLLKFLYKYHSNRADNELVRKYL 240
             :::       ||  |:::.....|..||:.:.||:.|.:......|.::..:.:..::...:.|
Mouse   179 -QVEKNSGGFVLP--PSYVPVILSGLGGQMTFTERVKNMICMLYFDFWFQTFTEKEWDQFYSETL 240

  Fly   241 GVEVD-VEEVARTQTAFIFGNQHYSLMGSRPQSLQFVE-IGGVHITKKAEQELPQNIANFLNQS- 302
            |.... :|.:.:.:..||  ..::.|....| :|..|| :||:|.  |..:.||:.:.:|:..|
Mouse   241 GRPTTLIETMGKAEMWFI--RSYWDLEFPHP-TLPNVEYVGGLHC--KPAKPLPKEMEDFVQSSG 300

  Fly   303 AEGVIFISWGSMVRASSIDEDKLSAILEVLKSQPLKIIWKWEADETPDTDASKFLFVKWAPQLAL 367
            ..||:..|.||||  |::.|::.:||...|...|.|::|:::. :||.:........||.||..|
Mouse   301 VHGVVVFSLGSMV--SNMTEERANAISWALAQIPQKVLWRFDG-KTPASLGPNTRIYKWLPQNDL 362

  Fly   368 LCHPKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDITVPNLKK 432
            |.|||.|.|.:|||..|..|::|.|.|::..|::.:|..|...:..:|..:.|:.:.::..:|..
Mouse   363 LGHPKTKAFVTHGGANGLYEAIHHGIPMIGIPLFSEQHDNIAHMVAKGTAVALNIRTMSRSDLLN 427

  Fly   433 ALAELSKN-SYAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGIELNGFVYHS 496
            ||.|:..| ||.:..:.:|.:.:::...||...|:.:|.|:.:.  .|:.|:.....|..:.|||
Mouse   428 ALEEVINNPSYKENVMWLSTIHHDQPMKPLNRTIFWIEFVMRHK--GAKHLRPLAHNLTWYQYHS 490

  Fly   497 LDSVALIL--------LPLILLILVLCYLCKR 520
            ||.:..:|        ||:...:.|..:..|:
Mouse   491 LDVIGFLLVCVVATAVLPVKCCLFVYQFFVKK 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_001285591.1	egt	8..475	CDD:223071	124/490 (25%)
		UDPGT	38..501	CDD:278624	127/486 (26%)
Ugt2b35	NP_766469.1	egt	8..506	CDD:223071	137/534 (26%)
		UDPGT	24..525	CDD:278624	136/526 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840159
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840