Protein Alignment Ugt36A1 and Ugt2b36

DIOPT Version :10

• Sequence 1: NP_524686.3
• Gene: Ugt36A1 / 44058
• FlyBaseID: FBgn0015663
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001025038.1
• Gene: Ugt2b36 / 231396
• MGIID: 3576103
• Length: 530
• Species: Mus musculus
• Alignment Length: 545
• Identity: 135/545 - (24%)
• Similarity: 255/545 - (46%)
• Gaps: 72/545 - (13%)

  Fly     1 MTTCLRSGVLIIVLLGILGIPEPISAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVI---- 61
            ::.|.||.                ..|.:| |:| ..:||:..:..||:||..:||::||:
Mouse    14 ISCCFRSA----------------KCGKVL-VWP-VDYSHWMNIKIILDELKQKGHEVTVLRPST 60

  Fly    62 SYVKNPQAGAYPNYE-----------ELLISAPGEDQS-----STTINLVPLTEHTPTRSLGVLI 110
            |...:|:......:|           |::.:...|..:     .|.::..||.::        :.
Mouse    61 SIFLDPKKSPGLKFETFPTSFSNDVMEIIFAKAVERWTYEVPRDTCLSYSPLLQN--------IF 117

  Fly   111 REYVDLHEEGQKTCEHLFASGHIERAIERHRNKPYDLLLTEYFNSDCQLALAKLLNLPIIGLSTC 175
            .||.|.   ....|:...::..:...::..:   :|::|::.. ..|...:|:||.:|.  |.:.
Mouse   118 DEYSDY---CLTLCKDTVSNKQLMAKLQESK---FDVILSDAI-GPCGELIAELLQIPF--LYSL 173

  Fly   176 ALMP-YYYDRID--LPDTPAFIQSEFVGFAGQLNWHERLLNFVQAKLLKFLYKYHSNRADNELVR 237
            ...| ||.::..  ||..|:::.....|.:||:.:.||:.|.:......|.::....:..::...
Mouse   174 RFSPGYYLEKYSGGLPLPPSYVPVILSGLSGQMTFKERVKNMICMLYFDFWFQTFREKKWDQFYS 238

  Fly   238 KYLGVEVD-VEEVARTQTAFIFGNQHYSLMGSRPQSLQFVEIGGVHITKKAEQELPQNIANFLNQ 301
            :.||.... :|.:.:.:...|  ..::.|....|.......:||||.  |..:.||:.:.:|:..
Mouse   239 ETLGRPTTLIETMGKAEMWLI--RSYWDLEFPHPTLPNVYYVGGVHC--KPAKPLPKEMEDFVQS 299

  Fly   302 SAE-GVIFISWGSMVRASSIDEDKLSAILEVLKSQPLKIIWKWEADETPDTDASKFLFVKWAPQL 365
            |.| ||:..|.||||  |::.|:|.:||...|...|.|::|:::. :||.|........||.||.
Mouse   300 SGEHGVVVFSLGSMV--SNMTEEKANAIAWALAQIPQKVLWRFDG-KTPATLGPNTRIYKWLPQN 361

  Fly   366 ALLCHPKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDITVPNL 430
            .||.|||.|.|.:|||..|..|::|.|.|::..|::|:|..|...:..:|..:.|:.:.::..:|
Mouse   362 DLLGHPKTKAFITHGGANGLYEAIHHGIPMIGIPLFGEQHDNIAHMVAKGAAVTLNIRTMSRSDL 426

  Fly   431 KKALAELSKNS-YAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGIELNGFVY 494
            ..||.|:..|. |.:.::.:|.:.:::...||:.|::.:|.|:.:.  .|:.|:.....|..:.|
Mouse   427 LNALEEVIDNPFYKENAMWLSTIHHDQPMKPLDRAVFWIEFVMRHK--GAKHLRPLAYNLTWYQY 489

  Fly   495 HSLDSVALIL--LPLILLILVLCYL 517
            ||||.:..:|  :..|:.::|.|:|
Mouse   490 HSLDVIGFLLAFVTFIVALIVKCFL 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_524686.3	GT1_Gtf-like	28..469	CDD:340817	116/466 (25%)
Ugt2b36	NP_001025038.1	UDPGT	24..527	CDD:278624	132/519 (25%)