Protein Alignment Ugt36A1 and Ugt1a2

DIOPT Version :10

• Sequence 1: NP_524686.3
• Gene: Ugt36A1 / 44058
• FlyBaseID: FBgn0015663
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_038729.1
• Gene: Ugt1a2 / 22236
• MGIID: 3576049
• Length: 533
• Species: Mus musculus
• Alignment Length: 561
• Identity: 146/561 - (26%)
• Similarity: 250/561 - (44%)
• Gaps: 78/561 - (13%)

  Fly    10 LIIVLLGILGI-----PEPISAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYVKNPQA 69
            |.:.|.||.|:     ..|.:.|..:.|.|..| |.:..:..::.||..|||...|::
Mouse     5 LCVPLRGISGLLLLLCALPWAEGAKVLVLPMEG-SQWLSMRDVVRELHARGHQTVVLA------- 61

  Fly    70 GAYPNYEELLISAPGEDQSSTTINLVPLTEHTPTRSL--------------------GVLIREYV 114
                  .|:.:...|||..:......|.|:....:.:                    ...||.:.
Mouse    62 ------SEVTVHIKGEDFFTLKTYAFPYTKEEYQQEILSDIEKTFKTQHFVKAFFETTASIRNFF 120

  Fly   115 DLHEEGQKTCEHLFASGHIERAIERHRNKPYDLLLTEYFNSDCQLALAKLLNLPIIGLSTCALMP 179
            ||:   ..:|..|.   |.:..|::..:..:|::||:.. ..|...|||.|.:|.:.:.......
Mouse   121 DLY---SNSCIALL---HNKMLIQQLNSSFFDVILTDPI-FPCGAVLAKYLQIPAVFILRSLSCG 178

  Fly   180 YYYDRIDLPDTPAFIQSEFVGFAGQLNWHERLLNFVQAKLLKFLYK-----YHSNRADNELVRKY 239
            ..|:....|:..::|.:.....:..:::.:|:.|.:...:||::.:     |.|      |..:.
Mouse   179 IEYEATQCPNPSSYIPNLLTRLSDHMDFLQRVQNMLYYLVLKYICRLSITPYES------LASEL 237

  Fly   240 LGVEVDVEEVARTQTAFIFGNQHYSLMGSRPQSLQFVEIGGVH-ITKKAEQELPQNIANFLNQSA 303
            |..||.:.||....:.::|... :.|...||.....|.|||:: :|||   .|.|....::|.|.
Mouse   238 LQREVSLVEVLSHASVWLFRGD-FVLDYPRPIMPNMVFIGGINCVTKK---PLSQEFEAYVNASG 298

  Fly   304 E-GVIFISWGSMVRASSIDEDKLSAILEVLKSQPLKIIWKWEADETPDTDASKFLFVKWAPQLAL 367
            | |::..|.||||  |.|.|.|...|.|.|...|..::|::.... |...|...:.|||.||..|
Mouse   299 EHGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTR-PSNLAKNTILVKWLPQNDL 360

  Fly   368 LCHPKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDITVPNLKK 432
            |.|||.:.|.:|.|..|..|.:..|.|:::.|::|||..||..::.||.|:.|:..::|..:|:.
Mouse   361 LGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLEN 425

  Fly   433 ALAELSKN-SYAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGIELNGFVYHS 496
            ||..:..| ||.:..:.:|.:..:|...||:.|::.||:|:.:.  .|..|:....:|..:.|||
Mouse   426 ALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHK--GAPHLRPAAHDLTWYQYHS 488

  Fly   497 LDSVALIL---LPLILLILVLC-YLCK-----RNPSKLAHK 528
            ||.:..:|   |.::.::...| |.|:     :...|.:||
Mouse   489 LDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_524686.3	GT1_Gtf-like	28..469	CDD:340817	120/468 (26%)
Ugt1a2	NP_038729.1	UDPGT	28..524	CDD:278624	136/531 (26%)