DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36A1 and ugt-55

DIOPT Version :9

Sequence 1:	NP_001285591.1	Gene:	Ugt36A1 / 44058	FlyBaseID:	FBgn0015663	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_506073.2	Gene:	ugt-55 / 188072	WormBaseID:	WBGene00011452	Length:	512	Species:	Caenorhabditis elegans

Alignment Length:	534	Identity:	127/534 - (23%)
Similarity:	210/534 - (39%)	Gaps:	80/534 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 PISAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYV---------------KNPQAGAY 72
            |..:..||...|....||...|..|.|.|..|||::.|:..|               |..:....
Worm    19 PCLSLRILVYSPRMIPSHVAFVANIANLLGQRGHNVVVVDNVLRSDISNKLDLKVIEKVVKVETS 83

  Fly    73 PNYEELLISAPGEDQSSTTINL-----VPLTEHTPTRSLGVLIREYVDLHEEGQKTCEHLFASGH 132
            .|..:||     .|| |..||.     .|..:....:.||::..|          .|::|.:..
Worm    84 ANVAKLL-----ADQ-SIPINFWSMRNEPEEQKKVMKQLGIIFLE----------QCKYLVSKE- 131

  Fly   133 IERAIERHRNKPYDLLLTEYFNSDCQLALAKLLNL-PIIGLSTCALMPYYYDRIDLPD--TPAFI 194
             |......::..:|..:.|.|:. |.:.:.:.|.: ..:.||:..:.....:.:.:..  ..|.|
Worm   132 -ETVFNELKHLEFDFGIHEVFDI-CGIGIFEKLGIRKSVILSSTGMRDIVNEALGISSQLQDASI 194

  Fly   195 QSE------FVGFAGQLNWHERLLNF--VQAKLLKFLYKYHSNRADNELVRKYLGVEVDVEEVAR 251
            .|:      |.|....|.:|....||  ||:|.|:.|::..|:                .|.:.|
Worm   195 LSDYGNSIPFYGIRRNLKFHSAWRNFFEVQSKTLEPLFETTSS----------------FENLLR 243

  Fly   252 TQTAFIFGNQHYSLMGSRPQSLQFVEIGGVHITKKAEQELPQNIANFLNQSAEGVIFISWGSMVR 316
            ... .:|.|.|......||.|.:..||||  |:.|....|.....|..|: ...:|.:|:|:...
Worm   244 FSN-LMFLNTHELADAHRPWSRRVHEIGG--ISFKFPMPLKNEYINLFNK-YNSIILVSFGTTTP 304

  Fly   317 ASSIDEDKLSAILEVLKSQP-LKIIWKWEADE--TPDTDASKFLFVKWAPQLALLCHPKVKLFWS 378
            :..:.|...:.::...:..| ...|||:|.|:  |........:|.|:.||:.||...|:|||.:
Worm   305 SFLMPEKYKNTLINTFQRFPDFLFIWKYEKDDEFTQKNKKGNVVFKKFLPQVDLLESRKIKLFIT 369

  Fly   379 HGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMG---LK--LDYQDITVPNLKKALAELS 438
            |||.....|:.|.....|:||::|||..||......|:.   ||  |..:::....:|:...  |
Worm   370 HGGQNSLLETFHSNTRTLITPLFGDQHRNAQIALENGLSHVLLKDQLANEELVYAAIKQGTE--S 432

  Fly   439 KNSYAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGIELNGFVYHSLDSVALI 503
            ........|::|......:||.....:.:||...::.|........|.:..:..:...|||:|:.
Worm   433 NKKLDDNLLKLSSNLKNAKQTSENLFLDTVESTYTDNLSPLNFEFYPKLYSSDQILLYLDSIAMF 497

  Fly   504 LLPLILLILVLCYL 517
            .|.|:.:||:..:|
Worm   498 TLTLLTMILIRKFL 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_001285591.1	egt	8..475	CDD:223071	116/490 (24%)
Ugt36A1	NP_001285591.1	UDPGT	38..501	CDD:278624	117/501 (23%)
ugt-55	NP_506073.2	UDPGT	35..>399	CDD:278624	98/402 (24%)
ugt-55	NP_506073.2	Glycosyltransferase_GTB_type	<247..>399	CDD:299143	47/154 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161453
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840