DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36A1 and ugt-13

DIOPT Version :9

Sequence 1:	NP_001285591.1	Gene:	Ugt36A1 / 44058	FlyBaseID:	FBgn0015663	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_504317.2	Gene:	ugt-13 / 186766	WormBaseID:	WBGene00019232	Length:	532	Species:	Caenorhabditis elegans

Alignment Length:	573	Identity:	146/573 - (25%)
Similarity:	240/573 - (41%)	Gaps:	118/573 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 ISAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYVKNPQAGAYPN-------------- 74
            :|:.|||...|.|||||.|.|..:...:|:.||::|:.    .|...|.||
Worm    15 VSSKNILIYDPIFGFSHVKFVSLMAEIIANHGHNVTLF----RPYHIALPNVDGLVKNKNIQIID 75

  Fly    75 -----YEELLISAPGEDQSSTTINLVPLTEHTPTRSLGV--LIREYVDLHEEGQKTCEHLFASGH 132
                 |:|||   ..|.|:.......||......|||.|  ||      ..|.::|...|...
Worm    76 YFPKHYDELL---HAEKQTFPGFWNDPLISQPVLRSLVVSKLI------SGEMKRTATQLLQD-- 129

  Fly   133 IERAIERHRNKPYDLLLTEYFNSDCQLALAKLLNLPIIGLSTCALMP--YYYDRIDLPDTPAFI- 194
             ||.:...|:|.:|::::|.|.. ..|.||.::::|.|     .:||  .|.|...|...|:.|
Worm   130 -ERVLNELRSKKFDVVISETFEI-TGLYLAHIIDVPCI-----PMMPAVRYLDLGYLLGQPSLIG 187

  Fly   195 --------QSEFVGFAGQLNWHERLLNFVQAKLLKFLYKYHSNRADNELVRKYLGVEVDV----- 246
                    .:...||..:||               .:|:|.....:.:...:|....::.
Worm   188 YAQQPGSKMAPEAGFLDRLN---------------DVYQYFFMSCETDWTSQYQNDNIEAAIGRP 237

  Fly   247 ----EEVARTQTAFIFGNQHYSLMGSRPQSLQFVEIGGVHITKKAEQELPQNIANFLNQSAEGV- 306
                :::.|....:|..:..| |..:.|.:...|::||:.:..|.    .:|:|. |::..|.:
Worm   238 LPNWKDLLRNSPIYILNSNPY-LDFAVPTTATIVQVGGMTVDLKK----MKNVAK-LSEEYETIL 296

  Fly   307 ------IFISWGSMVRASSIDEDKLSAILEVLKS-QPLKIIWKWEADETPDTDASKFL-----FV 359
                  :.||:||::|:..:.::....::::.:| ..:..|||:|..   |.:..|.|     ..
Worm   297 AERDYAVLISFGSVIRSFQMPDNFKVGLIKLFESLSDVTFIWKYEKG---DVEFQKRLPKNVHLK 358

  Fly   360 KWAPQLALLCHPKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQD 424
            ||.||.:||...:||||.:||||..|||..:.|||.|:.||:|||..||..:...|..:.  |..
Worm   359 KWVPQPSLLADKRVKLFVTHGGLGSTTEVAYTGKPALMVPIFGDQPNNADMLARHGGAIA--YSK 421

  Fly   425 ITVPNLKKALAELSKN-----SYAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQS 484
            ..:.|.:| ||...|:     .|.:::..:..|.:.:...|.|:.|..:|..:.   ......|.
Worm   422 FDLANGEK-LANTVKDMVFNPKYKEKAELLFDVLSNQPIDPKENFIKHLEFAMK---FPNHRSQV 482

  Fly   485 PGIELNGFV-YHSLDSVA-LILLPLILLILVLCYLCKRNPSKLAHKKVGKKPK 535
            |.:...|.: .:.||.:. .:::.||...|....||     :||....|||.|
Worm   483 PAVNQAGLIAQYYLDVIVFFVMISLISSYLSFVALC-----RLARVISGKKLK 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_001285591.1	egt	8..475	CDD:223071	130/509 (26%)
Ugt36A1	NP_001285591.1	UDPGT	38..501	CDD:278624	128/522 (25%)
ugt-13	NP_504317.2	egt	1..509	CDD:223071	136/545 (25%)
ugt-13	NP_504317.2	UDPGT	29..514	CDD:278624	131/536 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161502
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45374
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.850