DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36A1 and ugt-6

DIOPT Version :9

Sequence 1:	NP_001285591.1	Gene:	Ugt36A1 / 44058	FlyBaseID:	FBgn0015663	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001369960.1	Gene:	ugt-6 / 179755	WormBaseID:	WBGene00013904	Length:	533	Species:	Caenorhabditis elegans

Alignment Length:	557	Identity:	131/557 - (23%)
Similarity:	233/557 - (41%)	Gaps:	128/557 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 LAVYPHFGFSHFKVVMPILNELAHRGHDITVI-----------SYVKNPQAGAYPNYEELLISAP 83
            |.:.|.:||||.|.:..:.|.||..|:|:|..           :.:|......:..|.:.|
Worm    23 LVISPVYGFSHMKYMAELANHLARAGNDVTYFQPFVVDEYHDHTLIKEKSIKIWNYYHDEL---- 83

  Fly    84 GEDQSSTTINLVPLTEHTPTR----------------SLGVLIREYVDLHEEGQKTCEHLFASGH 132
            |.             :|.|::                ...:|:.:|  |....:..|..:|....
Worm    84 GR-------------QHIPSQGCMRDAWHSSWYQSDAGAAILLSKY--LFPAFEHMCRKMFEDTE 133

  Fly   133 IERAIERHRNKPYDLLLTEYFNSDCQLALAKLLNLPIIGLSTC------ALMPYYYDRIDLPDTP 191
            :...:   :::.:|::|:|.|:. |.|.||..|.:|.| :||.      ||.|...:       |
Worm   134 LHYDL---KSRQFDVVLSEAFDF-CGLYLASYLEMPSI-ISTFTGNRLNALAPVLGE-------P 186

  Fly   192 AFIQ------SEFVGFAG----QLN--WHERLLNFVQAKLLKFLYKYHSNRADNELVRKYLGVEV 244
            :|:.      |:: |...    :||  ||:...::..|:|.:..|:..| :..|..|:.:..:..
Worm   187 SFLHYLPAPTSQY-GHESTIFDRLNDVWHKIWSSYGFAQLFEMQYQQVS-KLTNGKVKHWKDIIH 249

  Fly   245 DVEEVARTQTAFIFGNQHYSLMGSRPQSLQFVEIGGVHI------TKKAEQELPQNIANFLNQSA 303
            ||        .:.|.|.:..|....|...:.|.|||:.:      |.....||.:::.|....:
Worm   250 DV--------TYHFSNSNPYLDFVIPTIPKVVPIGGITVDHDYWSTNGNHSELLEHVLNARKHN- 305

  Fly   304 EGVIFISWGSMVRASSIDEDKLSAILEVLKSQP-LKIIWKWEADETPDTDASKFL-----FVKWA 362
               :|||:|||||:..:.::...::::|....| :..:||:|...  |.:..:.|     ..||.
Worm   306 ---VFISFGSMVRSVDMPKEFKKSMMKVFSDHPNITFLWKYELPN--DQEFLRILPTNVHVAKWF 365

  Fly   363 PQLALLCHPKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRG---MGLKLDYQD 424
            .|.|||...:|.||.:||||..|.|.....||.:|.|::.||..||..::..|   :..|||
Worm   366 SQSALLSDQRVNLFVTHGGLGSTMELARAAKPAIVIPLFADQPGNAKMIERHGSVEIFSKLD--- 427

  Fly   425 ITVPNLKKALAELSK----NSYAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSP 485
              :||.||..:.:.|    ..|.|.:..::.....:..||.:..:...|:       |||..:.|
Worm   428 --IPNSKKLSSLIQKMLNTKYYQQNANRLADTLRFQPITPTDLMVKHAEN-------AARFGKMP 483

  Fly   486 GI-----ELNGFVYHSLDSVALILLPLILLILVLCYL 517
            .:     ::..|.|:::|.:.::.|.:.||..|:.::
Worm   484 NLVPHAKDMGFFEYYNIDIIFIVFLLVWLLFSVVAHV 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_001285591.1	egt	8..475	CDD:223071	120/508 (24%)
Ugt36A1	NP_001285591.1	UDPGT	38..501	CDD:278624	124/531 (23%)
ugt-6	NP_001369960.1	GT1_Gtf-like	20..456	CDD:340817	117/484 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45374
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920