DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36A1 and ugt-60

DIOPT Version :9

Sequence 1:	NP_001285591.1	Gene:	Ugt36A1 / 44058	FlyBaseID:	FBgn0015663	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001021158.1	Gene:	ugt-60 / 176366	WormBaseID:	WBGene00007402	Length:	507	Species:	Caenorhabditis elegans

Alignment Length:	533	Identity:	118/533 - (22%)
Similarity:	222/533 - (41%)	Gaps:	88/533 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 ILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYVKNPQAGAYPNYEELLISAPGEDQSSTTIN 93
            ||.:.|.|..||......:...|...|||:.:.:.:            |:.:...|.::....::
Worm    18 ILQIVPGFTNSHVLFNYRLAETLRFLGHDVKMWTQM------------EMAMLDTGNNKLPEGVS 70

  Fly    94 --LVPL--TEHTPTRSLGV---LIREYVDLHE---EGQ-------KTCEHLFASGHIERAIERHR 141
              .:|:  |:...|..|.|   ::.|..|.|:   .||       :.||.:..  |.|...|..|
Worm    71 EYRIPIHFTDTLKTEGLKVFQSMMFESGDAHDLWWTGQEFKDMRVEACEQMLR--HDESVYEDFR 133

  Fly   142 NKPYDLLLTEYFNSDCQLALAKLLNLPIIGLSTCALMPYYYDRIDL-----------PDTPAFIQ 195
            ...:|:.:. :|:..|.||:||.:|:..:...|.....|.:..:.|           |.:.|...
Worm   134 KDGFDVAIA-HFHDLCPLAIAKKMNVKRVIWITHGTSIYEFSAVQLGLRTIPSTIPHPLSSAGFS 197

  Fly   196 SEFVGFAGQLNWHERLLNFVQAKLLKFLYKYHSNRADNELV------RKYLGVEV-DVEEVARTQ 253
            ..|:.......||..||:||             |...|.||      |:::|.:. |:.::|:|.
Worm   198 QLFLDRVQNTLWHLSLLDFV-------------NLPQNLLVDENLFYREFVGADQDDLWDLAKTT 249

  Fly   254 TAFIFGNQHYSLMGSRPQSLQFVEIGGVHITKKAEQELPQNIANFLNQSAEGVIFISWGSMVRAS 318
            ...:..|....|...||..:.....|.:.::|..:..:.:.:.:.:.:.::|:|..|.|::...:
Worm   250 VPSLLINGDRMLDFPRPLPIHIAFSGELGVSKGKKLVMEKWLEDIIEKPSDGLIVFSLGTVSNTT 314

  Fly   319 SIDEDKLSAILEVL-KSQPLKIIWKWEADETPDTDASKFLFVKWAPQLALLCHPKVKLFWSHGGL 382
            ::....:::.|... |.:...|:|:.|..............|||.||..::.|||:||..:|||.
Worm   315 NMPAQMINSFLGAFGKLKTYTILWRMEKSVAGAEKYENLHLVKWLPQKDIMRHPKMKLMIAHGGY 379

  Fly   383 LGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDITVPNLKKALAELSKNSYAQRSL 447
            ....|:...|.|.::.|::.||.:||...|..||...||..|:|:.|:..|:.|..|..|:..:.
Worm   380 NSFLEAAQAGIPAVLMPLFADQKINAKRAQRYGMATVLDKLDLTINNVYGAIKEALKPEYSTNAK 444

  Fly   448 EVSKVFNER-QQTPLESAIWSVEHVISNGLIAARLLQSP--------GIELNGFVYHSLDSVALI 503
            ::|.:.::: .:.|..:..:|:           :|..||        ...|:...:|:||..:::
Worm   445 KLSAMLSDQVARKPYSALRYSL-----------KLATSPKPSLFTLKSQHLSFLEFHNLDIFSIV 498

  Fly   504 LLPLILLILVLCY 516
            |    |...::|:
Worm   499 L----LTAFIVCF 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_001285591.1	egt	8..475	CDD:223071	108/482 (22%)
Ugt36A1	NP_001285591.1	UDPGT	38..501	CDD:278624	111/507 (22%)
ugt-60	NP_001021158.1	Glycosyltransferase_GTB_type	17..>161	CDD:299143	36/157 (23%)
ugt-60	NP_001021158.1	egt	<253..464	CDD:223071	50/210 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910