DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36A1 and ugt5f1

DIOPT Version :9

Sequence 1:	NP_001285591.1	Gene:	Ugt36A1 / 44058	FlyBaseID:	FBgn0015663	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	XP_017207383.1	Gene:	ugt5f1 / 100415800	ZFINID:	ZDB-GENE-100406-6	Length:	556	Species:	Danio rerio

Alignment Length:	557	Identity:	150/557 - (26%)
Similarity:	264/557 - (47%)	Gaps:	77/557 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VLIIVLLGILGIPEPISAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYVKN---PQAG 70
            ::.:|.:.:|.:..|:..|.|| |:||.| ||:..:..::.||.||||.|:||..:.:   |:..
Zfish    34 IIFVVQIVVLSLTLPVHCGKIL-VFPHEG-SHWLNLNTLIEELHHRGHQISVIRALDSWYIPETS 96

  Fly    71 AYPNYEELLISAP----GEDQ---SSTTINLVPLTEHTPTR-SLGVLIRE-YVDLHEEGQKTCEH 126
              |:|:.  |:.|    |:||   |.....|....|...|| .|.:.::| :.::|   :|.||.
Zfish    97 --PHYDS--INVPFLLGGDDQFYHSFIFRQLQIRREQRWTRFKLDMELKEKFSEMH---RKICEM 154

  Fly   127 LFASGHIERAIERH-RNKPYDLLLTEYFNSDCQLALAKLLNLPII--------GLSTCALMPYYY 182
            :......|.||.:. :...:|::||:..|.. .:.||..|:||::        |.:..|:
Zfish   155 VIHIVEKEPAIMKQIKEANFDIMLTDPANGG-GVVLAHYLHLPLVFNVQWTVHGEAHFAI----- 213

  Fly   183 DRIDLPDTPAFIQSEFVGFAGQLNWHERLLNFVQAKLLKFLYKYHSNRADNELVRKYLGVEVDVE 247
                .|..|:::..........:::.:|:.|.:.:.:..|||:.......:.|..:..|..:|..
Zfish   214 ----APSPPSYVPFPLSQLTDSMSFPQRIYNVLFSAVRLFLYRRTVGPHYSALCNRLFGPGLDYF 274

  Fly   248 EVART------QTAFIFGNQHYSLMGSRPQSLQFVEIGGVHITKKAEQELPQNIANFLNQSAE-G 305
            |:.:.      :..|:|.       ..||.....:.|||.|.:  ..:.||:::.:||..|.| |
Zfish   275 ELFQAADIWLMRADFVFD-------FPRPTMPNVIYIGGFHCS--PAKALPKDLEDFLQSSGEHG 330

  Fly   306 VIFISWGSMVRASSID--EDKLSAILEVLKSQPLKIIWKWEADETPDTDASKFLFVKWAPQLALL 368
            ||.:|.|::|....:|  ::.::|..|:    |.|:||::..|. |....:..|.|.|.||..||
Zfish   331 VIVMSLGTLVAQLPMDIADEIVAAFAEL----PQKVIWRYTGDR-PANVGNNTLLVNWLPQNDLL 390

  Fly   369 CHPKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDITVPNLKKA 433
            .|||.::|.||||..|..|:::.|.|::..|:..||..|...::::|:...||...|.....|.|
Zfish   391 GHPKTRVFVSHGGTNGVFEAIYHGVPIVGLPLVFDQDYNLLKMKHKGVAKVLDIATINRNIFKDA 455

  Fly   434 LAE-LSKNSYAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGIELNGFVYHSL 497
            |.| |:..||.....::|.:..:....||:||::..|.|:.:.  .|..|::...::..:.|||:
Zfish   456 LQEVLNDPSYRSNMQKLSSLHKDTPLKPLDSALFWTEFVMRHR--GAAHLRTDSYKMPWYSYHSV 518

  Fly   498 DSVALILLPLILLILVL---------CYLC-KRNPSK 524
            | |.:.|:.::..|:.|         |..| |.|.:|
Zfish   519 D-VGVFLVSVLCFIVFLMFKIVRCLCCRFCAKTNRAK 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36A1	NP_001285591.1	egt	8..475	CDD:223071	135/496 (27%)
Ugt36A1	NP_001285591.1	UDPGT	38..501	CDD:278624	131/493 (27%)
ugt5f1	XP_017207383.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584301
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840