DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubc7 and UBE2G2

DIOPT Version :9

Sequence 1:	NP_001285334.1	Gene:	Ubc7 / 44054	FlyBaseID:	FBgn0267384	Length:	167	Species:	Drosophila melanogaster
Sequence 2:	NP_003334.2	Gene:	UBE2G2 / 7327	HGNCID:	12483	Length:	165	Species:	Homo sapiens

Alignment Length:	165	Identity:	135/165 - (81%)
Similarity:	153/165 - (92%)	Gaps:	0/165 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAGSALRRLMAEYKQLTLDPPEGIVAGPISEDNFFEWEALIAGPEGTCFEGGVFPARLIFPTDYP 65
            |||:||:|||||||||||:|||||||||::|:|||||||||.|||.||||.|||||.|.||.|||
Human     1 MAGTALKRLMAEYKQLTLNPPEGIVAGPMNEENFFEWEALIMGPEDTCFEFGVFPAILSFPLDYP 65

  Fly    66 LSPPKMKFTCDMFHPNIFADGRVCISILHAPGDDPMGYELSAERWSPVQSVEKILLSVVSMLAEP 130
            ||||||:|||:||||||:.||||||||||||||||||||.|||||||||||||||||||||||||
Human    66 LSPPKMRFTCEMFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLSVVSMLAEP 130

  Fly   131 NDESGANVDAAIMWREQRDEFNAIARRLVRKTLGL 165
            ||||||||||:.|||:.|::|..||:::|:|:|||
Human   131 NDESGANVDASKMWRDDREQFYKIAKQIVQKSLGL 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubc7	NP_001285334.1	COG5078	1..163	CDD:227410	132/161 (82%)
Ubc7	NP_001285334.1	UQ_con	8..159	CDD:278603	125/150 (83%)
UBE2G2	NP_003334.2	COG5078	1..163	CDD:227410	132/161 (82%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160526
Domainoid	1	1.000	266	1.000	Domainoid score	I1890
eggNOG	1	0.900	-	-		E1_KOG0426
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6599
Inparanoid	1	1.050	287	1.000	Inparanoid score	I2853
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55907
OrthoDB	1	1.010	-	-		D1317014at2759
OrthoFinder	1	1.000	-	-		FOG0005708
OrthoInspector	1	1.000	-	-		oto91139
orthoMCL	1	0.900	-	-		OOG6_105061
Panther	1	1.100	-	-	LDO	PTHR24067
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1585
SonicParanoid	1	1.000	-	-		X4106
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800