Protein Alignment Shc and C25A8.5

DIOPT Version :9

• Sequence 1: NP_524683.2
• Gene: Shc / 44052
• FlyBaseID: FBgn0015296
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_501081.1
• Gene: C25A8.5 / 182879
• WormBaseID: WBGene00016085
• Length: 416
• Species: Caenorhabditis elegans
• Alignment Length: 106
• Identity: 32/106 - (30%)
• Similarity: 58/106 - (54%)
• Gaps: 12/106 - (11%)

  Fly   296 LTAEVWFHAGISRPISERLLQQDGDFLVRESQGKRG---QYVLTG-----LEGKTPKHLLL-IDP 351
            :.:|.|:|..:.|...:.:|:::||||||.::.|.|   ||||:.     ||....||.:: ::|
 Worm     6 IPSEPWYHGLLPREDIKAMLRKNGDFLVRSTEPKAGEPRQYVLSAMQSEELEDAGVKHYVMRLNP 70

  Fly   352 EGVVRTKDRIFDSISHLINYHWAHALPIISEDSELVLRNPV 392
            ...:..:.:.|::|:.|:||:.....||   ....||:.|:
 Worm    71 SNQIFLEAKGFETIASLVNYYMNSKEPI---KKMTVLKTPI 108

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shc	NP_524683.2	PTB_Shc	19..178	CDD:269920
		SH2_SHC	293..396	CDD:198179	32/106 (30%)
C25A8.5	NP_501081.1	SH2_Fps_family	4..98	CDD:198224	27/91 (30%)
		TyrKc	120..374	CDD:197581
		PTKc	124..375	CDD:270623

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.861654	Normalized mean entropy	S5640
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860