Protein Alignment Pak and STE11

DIOPT Version :9

• Sequence 1: NP_001138013.2
• Gene: Pak / 44039
• FlyBaseID: FBgn0267698
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: NP_013466.1
• Gene: STE11 / 851076
• SGDID: S000004354
• Length: 717
• Species: Saccharomyces cerevisiae
• Alignment Length: 327
• Identity: 101/327 - (30%)
• Similarity: 167/327 - (51%)
• Gaps: 61/327 - (18%)

  Fly   546 DEEILEKLRTIVS----VGDPNRKYTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNL------- 599
            |.:...:...|||    :..| :.:.|...||.|:.|:||..:.:.||..:|:||:.:
Yeast   392 DHDFFGEDSDIVSLPTKIATP-KNWLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGV 455

  Fly   600 -----------------SQQPKKE--------------------LIINEILVMRENKHPNVVNYL 627
                             .||.|.|                    .:.:|:.:::|..|.|:|.|
Yeast   456 PTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTY- 519

  Fly   628 DSYLVSEE---LWVVMEYLPGGSLTDVVTE-TCMDEGQIAAVCREVLQALEFLHANQVIHRDIKS 688
              |..|:|   |.:.:||:||||::.::.. ...:|..|....|::|..:.:||...:||||||.
Yeast   520 --YGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKG 582

  Fly   689 DNILLGLDGSVKLTDFGFCAQISP---EQSKRTTMVGTPYWMAPEVVTRKQYGPKVDLWSLGIMA 750
            .|||:.:.|.||:||||...::||   :|:||.::.|:.:||:||||.:.....|.|:||.|.:.
Yeast   583 ANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVV 647

  Fly   751 IEMVEGEPPYLNENPLKALYLIATNGKPEIKEKDKLSSAFQDFLDQCLEVEVDRRASALDLLKHP 815
            |||..|:.|:.:.:.::|::.|.||..|||  ....:|..::||.:..|::...|.|||:||:||
Yeast   648 IEMFTGKHPFPDFSQMQAIFKIGTNTTPEI--PSWATSEGKNFLRKAFELDYQYRPSALELLQHP 710

  Fly   816 FL 817
            :|
Yeast   711 WL 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pak	NP_001138013.2	PBD	83..137	CDD:279166
		STKc_PAK_I	558..818	CDD:270814	98/315 (31%)
		S_TKc	566..817	CDD:214567	95/301 (32%)
STE11	NP_013466.1	SAM_Ste11_fungal	20..82	CDD:188933
		Ras_bdg_2	121..224	CDD:405528
		PKc_like	415..712	CDD:419665	95/301 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910