DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak and MAPKKK16

DIOPT Version :9

Sequence 1:	NP_001138013.2	Gene:	Pak / 44039	FlyBaseID:	FBgn0267698	Length:	840	Species:	Drosophila melanogaster
Sequence 2:	NP_194419.2	Gene:	MAPKKK16 / 828796	AraportID:	AT4G26890	Length:	444	Species:	Arabidopsis thaliana

Alignment Length:	261	Identity:	90/261 - (34%)
Similarity:	148/261 - (56%)	Gaps:	21/261 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   566 YTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQQPKKELIINEILVMRENKHPNVVNYLDSY 630
            :|:...||:|::.||..|| ||:|...|:|..:||   ...|:..|..::.....|::|.|:.:.
plant     5 WTRGPIIGRGSTATVSIAI-SSSGELFAVKSADLS---SSSLLQKEQSILSTLSSPHMVKYIGTG 65

  Fly   631 LVSEELWVV----MEYLPGGSLTDVVTET--CMDEGQIAAVCREVLQALEFLHANQVIHRDIKSD 689
            |..|...:|    |||:.||:|.|::..:  .:.|.:|.:..|::|..|.:||...::|.|:||.
plant    66 LTRESNGLVYNILMEYVSGGNLHDLIKNSGGKLPEPEIRSYTRQILNGLVYLHERGIVHCDLKSH 130

  Fly   690 NILLGLDGSVKLTDFGFCAQISPEQSKRTTMVGTPYWMAPEVVTRKQYGPKVDLWSLGIMAIEMV 754
            |:|:..:|.:|:.|.| ||: |.::|:   ..|||.:|||||...::.....|:|:||...|||:
plant   131 NVLVEENGVLKIADMG-CAK-SVDKSE---FSGTPAFMAPEVARGEEQRFPADVWALGCTMIEMM 190

  Fly   755 EGEPPY--LNENPLKALYLIATNGK-PEIKEKDKLSSAFQDFLDQCLEVEVDRRASALDLLKHPF 816
            .|..|:  ||: .:.|:|.|..:|: |.|..  .:|...:|||..||:.:..:|.:..:||||||
plant   191 TGSSPWPELND-VVAAMYKIGFSGESPAIPA--WISDKAKDFLKNCLKEDQKQRWTVEELLKHPF 252

  Fly   817 L 817
            |
plant   253 L 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak	NP_001138013.2	PBD	83..137	CDD:279166
		STKc_PAK_I	558..818	CDD:270814	90/261 (34%)
		S_TKc	566..817	CDD:214567	88/259 (34%)
MAPKKK16	NP_194419.2	STKc_MAPKKK	4..253	CDD:270783	88/259 (34%)
MAPKKK16	NP_194419.2	S_TKc	5..253	CDD:214567	88/259 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910