DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak and MAPKKK7

DIOPT Version :9

Sequence 1:	NP_001138013.2	Gene:	Pak / 44039	FlyBaseID:	FBgn0267698	Length:	840	Species:	Drosophila melanogaster
Sequence 2:	NP_187962.1	Gene:	MAPKKK7 / 820555	AraportID:	AT3G13530	Length:	1368	Species:	Arabidopsis thaliana

Alignment Length:	305	Identity:	107/305 - (35%)
Similarity:	164/305 - (53%)	Gaps:	18/305 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   542 KKMSDEEILEKLRTIVSVGDPNRKYTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQQPKKE 606
            ::|:..: ..|.:|:      :.||...::||:||.|.||..::...|..|||||::|....:::
plant     3 RQMTSSQ-FHKSKTL------DNKYMLGDEIGKGAYGRVYKGLDLENGDFVAIKQVSLENIVQED 60

  Fly   607 L--IINEILVMRENKHPNVVNYLDSYLVSEELWVVMEYLPGGSLTDVVTET---CMDEGQIAAVC 666
            |  |:.||.:::...|.|:|.||.|......|.:::||:..|||.:::...   ...|..:|...
plant    61 LNTIMQEIDLLKNLNHKNIVKYLGSSKTKTHLHIILEYVENGSLANIIKPNKFGPFPESLVAVYI 125

  Fly   667 REVLQALEFLHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPEQSKRTTMVGTPYWMAPEV 731
            .:||:.|.:||...|||||||..|||...:|.|||.|||...:::.......::|||||||||||
plant   126 AQVLEGLVYLHEQGVIHRDIKGANILTTKEGLVKLADFGVATKLNEADVNTHSVVGTPYWMAPEV 190

  Fly   732 VTRKQYGPKVDLWSLGIMAIEMVEGEPPYLNENPLKALYLIATNGKPEIKEKDKLSSAFQDFLDQ 796
            :.........|:||:|...||::...|||.:..|:.||:.|..:..|.|  .|.||....|||.|
plant   191 IEMSGVCAASDIWSVGCTVIELLTCVPPYYDLQPMPALFRIVQDDNPPI--PDSLSPDITDFLRQ 253

  Fly   797 CLEVEVDRRASALDLLKHPFLKLARPL--ASL--TPLIMAAKEAT 837
            |.:.:..:|..|..||.||:::.:|..  :||  :..|...||||
plant   254 CFKKDSRQRPDAKTLLSHPWIRNSRRALQSSLRHSGTIKYMKEAT 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak	NP_001138013.2	PBD	83..137	CDD:279166
		STKc_PAK_I	558..818	CDD:270814	96/264 (36%)
		S_TKc	566..817	CDD:214567	95/255 (37%)
MAPKKK7	NP_187962.1	STKc_Cdc7_like	19..274	CDD:270797	96/256 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910