DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak and Stk26

DIOPT Version :9

Sequence 1:	NP_001138013.2	Gene:	Pak / 44039	FlyBaseID:	FBgn0267698	Length:	840	Species:	Drosophila melanogaster
Sequence 2:	NP_598490.1	Gene:	Stk26 / 70415	MGIID:	1917665	Length:	416	Species:	Mus musculus

Alignment Length:	275	Identity:	116/275 - (42%)
Similarity:	174/275 - (63%)	Gaps:	4/275 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   558 SVGDPNRKYTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQ-QPKKELIINEILVMRENKHP 621
            ::.||...:||:|:||:|:.|.|:..|::.|...||||.::|.: :.:.|.|..||.|:.:....
Mouse    16 NIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSS 80

  Fly   622 NVVNYLDSYLVSEELWVVMEYLPGGSLTDVVTETCMDEGQIAAVCREVLQALEFLHANQVIHRDI 686
            .|..|..|||...:||::||||.|||..|::.....||.|||.:.:|:|:.|::||:.:.|||||
Mouse    81 YVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDI 145

  Fly   687 KSDNILLGLDGSVKLTDFGFCAQISPEQSKRTTMVGTPYWMAPEVVTRKQYGPKVDLWSLGIMAI 751
            |:.|:||...|.|||.|||...|::..|.||.|.||||:||||||:.:..|..|.|:|||||.||
Mouse   146 KAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAI 210

  Fly   752 EMVEGEPPYLNENPLKALYLIATNGKPEIKEKDKLSSAFQDFLDQCLEVEVDRRASALDLLKHPF 816
            |:.:||||..:.:|::.|:||..|..|.:  ....:.:|::|:|.||..:...|.:|.:||||.|
Mouse   211 ELAKGEPPNSDMHPMRVLFLIPKNNPPTL--IGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKF 273

  Fly   817 L-KLARPLASLTPLI 830
            : |.::..:.||.||
Mouse   274 IVKNSKKTSYLTELI 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak	NP_001138013.2	PBD	83..137	CDD:279166
		STKc_PAK_I	558..818	CDD:270814	111/261 (43%)
		S_TKc	566..817	CDD:214567	108/251 (43%)
Stk26	NP_598490.1	STKc_MST4	19..295	CDD:132971	116/272 (43%)
		S_TKc	24..274	CDD:214567	108/251 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	296..343
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910