DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak and oxsr1a

DIOPT Version :9

Sequence 1:	NP_001138013.2	Gene:	Pak / 44039	FlyBaseID:	FBgn0267698	Length:	840	Species:	Drosophila melanogaster
Sequence 2:	NP_001092217.1	Gene:	oxsr1a / 568602	ZFINID:	ZDB-GENE-070620-25	Length:	515	Species:	Danio rerio

Alignment Length:	292	Identity:	114/292 - (39%)
Similarity:	161/292 - (55%)	Gaps:	31/292 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   561 DPNRK--------YTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQ-QPKKELIINEILVMR 616
            ||:.:        |...|.||.||:..|..|.......:||||::||.: |...:.::.||..|.
Zfish     4 DPSSQPWSIDKDDYELQEVIGSGATAVVQAAYCKPRKEKVAIKRINLEKCQTSMDELLKEIQAMS 68

  Fly   617 ENKHPNVVNYLDSYLVSEELWVVMEYLPGGSLTDVV---------TETCMDEGQIAAVCREVLQA 672
            :..|||:|:|..|::|.:|||:||:.|.|||:.|.:         ....|||..||.:.||||:.
Zfish    69 QCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDFIKYIISKGEHKSGVMDEPSIATILREVLEG 133

  Fly   673 LEFLHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQIS-----PEQSKRTTMVGTPYWMAPEVV 732
            ||:||.|..||||:|:.|||||.||||::.|||..|.::     .....|.|.||||.||||||:
Zfish   134 LEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDMTRNKVRKTFVGTPCWMAPEVM 198

  Fly   733 TR-KQYGPKVDLWSLGIMAIEMVEGEPPYLNENPLKALYLIATNGKP----EIKEKD---KLSSA 789
            .: :.|..|.||||.||.|||:..|..||....|:|.|.|...|..|    .:.:|:   |...:
Zfish   199 EQVRGYDFKADLWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPCLETGVTDKEMVKKYGKS 263

  Fly   790 FQDFLDQCLEVEVDRRASALDLLKHPFLKLAR 821
            |:..:..||:.:.::|.:|.:||||.|...|:
Zfish   264 FRKMISLCLQKDPEKRPTAAELLKHKFFTKAK 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak	NP_001138013.2	PBD	83..137	CDD:279166
		STKc_PAK_I	558..818	CDD:270814	113/287 (39%)
		S_TKc	566..817	CDD:214567	110/273 (40%)
oxsr1a	NP_001092217.1	STKc_OSR1_SPAK	15..291	CDD:270787	110/275 (40%)
oxsr1a	NP_001092217.1	S_TKc	17..291	CDD:214567	110/273 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910