Protein Alignment Pak and pak6b

DIOPT Version :9

• Sequence 1: NP_001138013.2
• Gene: Pak / 44039
• FlyBaseID: FBgn0267698
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: NP_001155959.1
• Gene: pak6b / 567874
• ZFINID: ZDB-GENE-041014-121
• Length: 607
• Species: Danio rerio
• Alignment Length: 801
• Identity: 238/801 - (29%)
• Similarity: 344/801 - (42%)
• Gaps: 224/801 - (27%)

  Fly    60 RKKKTLKSKIKGSKPSHTDSKPNISYPTNFEHTVHVGFDAVTGEFTGMPEAWARLLMNSNISKQE 124
            ||||  |.|::            ||.|.||:|.||..||.|.|.|.|:|..|..|:        |
Zfish     5 RKKK--KRKLE------------ISTPKNFQHRVHTSFDPVQGCFIGLPPQWQSLI--------E 47

  Fly   125 QKKNPQAVLDVLKWFDNTTKQRPSSKYMTNAITTHSG------SSLSRVSSSSPSSTPTDSELHG 183
            ..|.|:.|:|...:  ...:.||....:..:...|..      :.:||:|.:|
Zfish    48 TLKRPKPVVDPSSF--TQVQVRPQKSIVRGSFIGHEDYISAAIAQMSRLSVTS------------ 98

  Fly   184 SNSGGNLIGVQLGSMTLGPNANNVAVAGQILGNHYQQQQQHLLQQQQPLLHQNHNQHHMGISQSH 248
            |||      ::..|.::...|.::...|::     .:.:.:..::.....|:|.:..|.|....
Zfish    99 SNS------LRRRSPSVRKRAQSLGRLGEL-----AEAETYEYEELNNTNHRNSSDLHRGSRPI- 151

  Fly   249 SYNFVGHTVSSSTSQHSSANEDDMLGPQHPQQQPPPPPVASRPERTKSIYTRPIEDLQPAIIPMP 313
                                       |.||.:....|..:|.....:::|        .::|..
Zfish   152 ---------------------------QSPQTESRQSPARARSVHEATMFT--------GLMPRD 181

  Fly   314 VAPATTPATPLQNHRTPGGISAPAASPMMHNNATTTLDK--NKNNATPTSPTTTKTTA------- 369
            :                          ::|.......|.  ||.|..|.|...:::..
Zfish   182 I--------------------------LLHRAGCEGTDNAGNKPNQRPVSCLYSQSDGAKLNSDQ 220

  Fly   370 ---ETEGTDATSTLLSATNPSCSTTPTTDPAPAAPRGSLVETATAHATTAAATVATSTTTNHHSS 431
               ||:....::......:|:.       ||.:.|.|                  ||:....|.
Zfish   221 LKMETQRRPQSTYDFKVNSPNL-------PAASKPNG------------------TSSPKPGHG- 259

  Fly   432 ASSFSSFPSFHDDDGTHHALPTIHCPTPTSSSRNSTV---SFPVAVPLPPIVTPASP--TPASIE 491
                                 .|...||..||.::|:   :.|..|| |...:|:.|  .|:...
Zfish   260 ---------------------IISMQTPRRSSTDNTLKLSTIPADVP-PAQDSPSEPRQAPSGAS 302

  Fly   492 SPDLYTPEPTVAQVSAGGPSSQVAGNQIAVPQAAVAPAATPNTRAANAKKKKMSDEEILEKLRTI 556
            ||.|..|..|..|.                             |||               |:.:
Zfish   303 SPGLTEPSVTHTQF-----------------------------RAA---------------LQMV 323

  Fly   557 VSVGDPNRKYTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQQPKKELIINEILVMRENKHP 621
            |..|||........|||:|::|.|..|.|..:|.:||:|.|:|.:|.::||:.||:::||:.:|.
Zfish   324 VDPGDPRSYLENFIKIGEGSTGVVCIAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYRHQ 388

  Fly   622 NVVNYLDSYLVSEELWVVMEYLPGGSLTDVVTETCMDEGQIAAVCREVLQALEFLHANQVIHRDI 686
            |||....|.||.|||||:||||.||:||::|:||.:.|.|||.||..|||||.:||:..||||||
Zfish   389 NVVEMYKSALVGEELWVIMEYLQGGALTNIVSETRLTEEQIATVCESVLQALCYLHSQGVIHRDI 453

  Fly   687 KSDNILLGLDGSVKLTDFGFCAQISPEQSKRTTMVGTPYWMAPEVVTRKQYGPKVDLWSLGIMAI 751
            |||:|||.|||.|||:|||||||||.:..||.::||||||||||||::..||.:||:||||||.:
Zfish   454 KSDSILLTLDGRVKLSDFGFCAQISKDVPKRRSLVGTPYWMAPEVVSKTPYGTEVDIWSLGIMVV 518

  Fly   752 EMVEGEPPYLNENPLKALYLIATNGKPEIKEKDKLSSAFQDFLDQCLEVEVDRRASALDLLKHPF 816
            |||:|||||.:|.|:.|:..:.....|..:...|:|...:||||..|..|..:|:||.|||:|||
Zfish   519 EMVDGEPPYFSETPISAMKRLRDEPPPTARNASKISPVLRDFLDSMLTREPQQRSSASDLLQHPF 583

  Fly   817 LKLARPLASLTPLIMAAKEAT 837
            |........|.||:...:..|
Zfish   584 LLQCSSPRCLIPLVEQTRRRT 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pak	NP_001138013.2	PBD	83..137	CDD:279166	22/53 (42%)
		STKc_PAK_I	558..818	CDD:270814	140/259 (54%)
		S_TKc	566..817	CDD:214567	136/250 (54%)
pak6b	NP_001155959.1	PBD	13..65	CDD:279166	22/73 (30%)
		STKc_PAK6	311..607	CDD:270821	152/338 (45%)
		S_TKc	338..584	CDD:214567	136/245 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D757766at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920