DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak and hppy

DIOPT Version :9

Sequence 1:	NP_001138013.2	Gene:	Pak / 44039	FlyBaseID:	FBgn0267698	Length:	840	Species:	Drosophila melanogaster
Sequence 2:	NP_725863.1	Gene:	hppy / 37203	FlyBaseID:	FBgn0263395	Length:	1218	Species:	Drosophila melanogaster

Alignment Length:	283	Identity:	118/283 - (41%)
Similarity:	170/283 - (60%)	Gaps:	12/283 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   553 LRTIVSVGDPNRKYTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQQPKKELIINEILVMRE 617
            |.:.:|..:|..:|..::|||.|..|.||.|....:....|||.:.|......::|..||::||:
  Fly    13 LSSDISRRNPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRD 77

  Fly   618 NKHPNVVNYLDSYLVSEELWVVMEYLPGGSLTDVVTET-CMDEGQIAAVCREVLQALEFLHANQV 681
            .:|||::.|..|||..::||:.||:..||||.|:...| .:.|.|||.:|||.|:.||:||:...
  Fly    78 CRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGK 142

  Fly   682 IHRDIKSDNILLGLDGSVKLTDFGFCAQISPEQSKRTTMVGTPYWMAPEV--VTRK-QYGPKVDL 743
            :|||||..||||...|.|||.|||..|||:...:||.:.:||||||||||  |.|| .|....|:
  Fly   143 MHRDIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDI 207

  Fly   744 WSLGIMAIEMVEGEPPYLNENPLKALYLIATNG--KPEIKEKDKLSSAFQDFLDQCLEVEVDRRA 806
            |:.||.|||:.|.:||..:.:|::||:|::.:|  .|.:..|||.|..|.:|:...|.....:|.
  Fly   208 WACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRP 272

  Fly   807 SALDLLKHPF------LKLARPL 823
            :|..||:|||      |::|:.|
  Fly   273 TAERLLQHPFVQCEMSLRVAKEL 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak	NP_001138013.2	PBD	83..137	CDD:279166
		STKc_PAK_I	558..818	CDD:270814	114/271 (42%)
		S_TKc	566..817	CDD:214567	112/262 (43%)
hppy	NP_725863.1	STKc_MAP4K3_like	25..283	CDD:270788	111/257 (43%)
		S_TKc	26..283	CDD:214567	111/256 (43%)
		CNH	869..1184	CDD:279162
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438537
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840