Protein Alignment Pak and pak2b

DIOPT Version :10

• Sequence 1: NP_001138013.2
• Gene: Pak / 44039
• FlyBaseID: FBgn0267698
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: NP_001020627.2
• Gene: pak2b / 325034
• ZFINID: ZDB-GENE-030131-3759
• Length: 537
• Species: Danio rerio
• Alignment Length: 841
• Identity: 350/841 - (41%)
• Similarity: 421/841 - (50%)
• Gaps: 317/841 - (37%)

  Fly     5 EDKPPAPPVRLTSN--RGGNERSGGGVGVGGGGLGGGGMGDVPPDMRPLPKEPDDSDRKK--KTL 65
            ||||||||||::|.  .|..:.:                .......:|||..|::..|.|  ...
Zfish     8 EDKPPAPPVRMSSTIFSGAKDHA----------------LTANHSSKPLPSVPEERKRNKIYSIF 56

  Fly    66 KSKIKGSKPSHTD-SKPNISYPTNFEHTVHVGFDAVTGEFTGMPEAWARLLMNSNISKQEQKKNP 129
            ....||.:....| .:|.||.|::||||:||||||||||||||||.|||||..|||:|.||||||
Zfish    57 SGAEKGGRRKDRDKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKNP 121

  Fly   130 QAVLDVLKWFDNTTKQRPSSKYMTNAITTHSGSSLSRVSSSSPSSTPTDSELHGSNSGGNLIGVQ 194
            ||||||||::|:|...|  .||:          |.|....|.||.
Zfish   122 QAVLDVLKFYDSTGNGR--QKYL----------SFSSEKDSFPSG-------------------- 154

  Fly   195 LGSMTLGPNANNVAVAGQILGNHYQQQQQHLLQQQQPLLHQNHNQHHMGISQSHSYNFVGHTVSS 259
                                      :|....:..:|                      ...|.:
Zfish   155 --------------------------EQSPAKKTPEP----------------------SSPVKA 171

  Fly   260 STSQHSSANEDDMLGPQHPQQQPPPPPVASRPERTKSIYTRPIEDLQPAIIPMPVAPATTPATPL 324
            ...:.:..:|||     ...::.|||.||.|||.|||:||||
Zfish   172 VDDEDNGEDEDD-----DDDEETPPPVVAPRPEHTKSVYTRP----------------------- 208

  Fly   325 QNHRTPGGISAPAASPMMHNNATTTLDKNKNNATPTSPTTTKTTAETEGTDATSTLLSATNPSCS 389
                                                                             
Zfish   209 ----------------------------------------------------------------- 208

  Fly   390 TTPTTDPAPAAPRGSLVETATAHATTAAATVATSTTTNHHSSASSFSSFPSFHDDDGTHHALPTI 454
                          |:::
Zfish   209 --------------SVID----------------------------------------------- 212

  Fly   455 HCPTPTSSSRNSTVSFPVAVPLPPIVTPASPTPASIESPDLYTPEPTVAQVSAGGPSSQVAGNQI 519
                                ||||.||.
Zfish   213 --------------------PLPPPVTS------------------------------------- 220

  Fly   520 AVPQAAVAPAATPNTRAANAKKKKMSDEEILEKLRTIVSVGDPNRKYTKMEKIGQGASGTVYTAI 584
              |::..|..||...|   .||.||:||||::|||||||:|||.:|||:.|||||||||||:|||
Zfish   221 --PESDAASKATDRQR---PKKGKMTDEEIMDKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTAI 280

  Fly   585 ESSTGMEVAIKQMNLSQQPKKELIINEILVMRENKHPNVVNYLDSYLVSEELWVVMEYLPGGSLT 649
            :.:||.||||||:||.:||||||||||||||:|.|:||:||:|||:||.|||:||||||.|||||
Zfish   281 DVATGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSFLVGEELFVVMEYLAGGSLT 345

  Fly   650 DVVTETCMDEGQIAAVCREVLQALEFLHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPEQ 714
            ||||||||||.||||||||.|||||||||||||||||||||:|||:|||||||||||||||:|||
Zfish   346 DVVTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMDGSVKLTDFGFCAQITPEQ 410

  Fly   715 SKRTTMVGTPYWMAPEVVTRKQYGPKVDLWSLGIMAIEMVEGEPPYLNENPLKALYLIATNGKPE 779
            |||:|||||||||||||||||.||||||:|||||||||||||||||||||||:|||||||||.||
Zfish   411 SKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPE 475

  Fly   780 IKEKDKLSSAFQDFLDQCLEVEVDRRASALDLLKHPFLKLARPLASLTPLIMAAKEATKGN 840
            ::..:|||..|:|||.:|||::|::|..:.:||:|||||||:||:||||||:|||:|.|.|
Zfish   476 LQSPEKLSPIFRDFLGRCLEMDVEKRGGSKELLQHPFLKLAKPLSSLTPLILAAKDAMKNN 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pak	NP_001138013.2	PBD	83..139	CDD:395634	46/55 (84%)
		STKc_PAK_I	558..818	CDD:270814	207/259 (80%)
pak2b	NP_001020627.2	None