| Sequence 1: | NP_001138013.2 | Gene: | Pak / 44039 | FlyBaseID: | FBgn0267698 | Length: | 840 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_058894.1 | Gene: | Pak1 / 29431 | RGDID: | 3250 | Length: | 544 | Species: | Rattus norvegicus |
| Alignment Length: | 842 | Identity: | 375/842 - (44%) |
|---|---|---|---|
| Similarity: | 435/842 - (51%) | Gaps: | 313/842 - (37%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 5 EDKPPAPPVRLTSNRGGNERSGGGVGVGG---GGLGGGGMGDVPPDMRPLPKEPDDSDRKKKTLK 66
Fly 67 SKIKGSKPSHTDSK--PNISYPTNFEHTVHVGFDAVTGEFTGMPEAWARLLMNSNISKQEQKKNP 129
Fly 130 QAVLDVLKWFDNTTKQRPSSKYMTNAITTHSGSSLSRVSSSSPSSTPTDSELHGSNSGGNLIGVQ 194
Fly 195 LGSMTLGPNANNVAVAGQILGNHYQQQQQHLLQQQQPLLHQNHNQHHMGISQSHSYNFVGHTVSS 259
Fly 260 STS-QHSSANEDDMLGPQHPQQQPPPPPVASRPERTKSIYTRPIEDLQPAIIPMPVAPATTPATP 323
Fly 324 LQNHRTPGGISAPAASPMMHNNATTTLDKNKNNATPTSPTTTKTTAETEGTDATSTLLSATNPSC 388
Fly 389 STTPTTDPAPAAPRGSLVETATAHATTAAATVATSTTTNHHSSASSFSSFPSFHDDDGTHHALPT 453
Fly 454 IHCPTPTSSSRNSTVSFPVAVPLPPIVTPASPTPASIESPDLYTPEPTVAQVSAGGPSSQVAGNQ 518
Fly 519 IAVPQAAVAPAATPNTRAANAKKKKMSDEEILEKLRTIVSVGDPNRKYTKMEKIGQGASGTVYTA 583
Fly 584 IESSTGMEVAIKQMNLSQQPKKELIINEILVMRENKHPNVVNYLDSYLVSEELWVVMEYLPGGSL 648
Fly 649 TDVVTETCMDEGQIAAVCREVLQALEFLHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPE 713
Fly 714 QSKRTTMVGTPYWMAPEVVTRKQYGPKVDLWSLGIMAIEMVEGEPPYLNENPLKALYLIATNGKP 778
Fly 779 EIKEKDKLSSAFQDFLDQCLEVEVDRRASALDLLKHPFLKLARPLASLTPLIMAAKEATKGN 840 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Pak | NP_001138013.2 | PBD | 83..137 | CDD:279166 | 44/53 (83%) |
| STKc_PAK_I | 558..818 | CDD:270814 | 215/259 (83%) | ||
| S_TKc | 566..817 | CDD:214567 | 208/250 (83%) | ||
| Pak1 | NP_058894.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..79 | 27/86 (31%) | |
| Autoregulatory region | 70..140 | 49/70 (70%) | |||
| GTPase-binding | 70..105 | 26/34 (76%) | |||
| PBD | 74..132 | CDD:395634 | 45/58 (78%) | ||
| Interaction with CRIPAK. /evidence=ECO:0000250 | 132..269 | 76/425 (18%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 150..195 | 18/112 (16%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 209..250 | 25/233 (11%) | |||
| STKc_PAK1 | 248..543 | CDD:270820 | 245/294 (83%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C166343815 | |
| Domainoid | 1 | 1.000 | 443 | 1.000 | Domainoid score | I513 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H1936 | |
| Inparanoid | 1 | 1.050 | 668 | 1.000 | Inparanoid score | I711 |
| OMA | 1 | 1.010 | - | - | QHG52925 | |
| OrthoDB | 1 | 1.010 | - | - | D425477at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000763 | |
| OrthoInspector | 1 | 1.000 | - | - | otm46435 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100484 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR48015 |
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 1 | 1.000 | - | - | X799 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.910 | |||||